Discussion Piperacillin/tazobactam is a b-lactam/b-lactamase inhibitor combination with a
broad spectrum of antibacterial activity against most gram-positive and gram-negative …

Therapeutic drug monitoring for critically ill patients receiving piperacillin/tazobactam is
described as a useful tool. However, the minimum inhibitory concentration of piperacillin …

Abstract Piperacillin-tazobactam (PIP-TAZ) is commonly used to treat intraabdominal
infections; however, its penetration into abdominal sites is unclear. A pharmacokinetic …

A rapid and sensitive reverse phase HPLC (RP-HPLC) method for the simultaneous
quantitation of piperacillin and tazobactam in human plasma has been developed and …

The study objective was to evaluate the population pharmacokinetics and
pharmacodynamics of extended-infusion piperacillin-tazobactam in children hospitalized in …

Introduction To enhance the probability of pharmacodynamic target attainment, piperacillin–
tazobactam can be administered as either a continuous or extended-infusion dosage …

Piperacillin/tazobactam is a β-lactam/β-lactamase inhibitor combination with a broad
spectrum of antibacterial activity encompassing most Gram-positive and Gram-negative …

We reviewed the spectrum of activity, pharmacokinetics, clinical efficacy, adverse effects,
and relative advantages of piperacillin‐tazobactam, a new β‐lactam‐β‐lactamase inhibitor …

Purpose The development and implementation of an extended-infusion piperacillin–
tazobactam program at an urban teaching hospital are described. Summary A …

Piperacillin in combination with tazobactam is one of the most commonly used intravenous
antibiotics. There is evidence for a possible saturable elimination of piperacillin. Therefore …