The percentage of the time that the free drug concentration remains above a concentration
threshold (% fT> concentration threshold) has frequently been identified to be the optimal …

Piperacillin sodium–tazobactam sodium, a β-lactam antimicrobial, is extensively used
because of its broad-spectrum activity against many enteric gram-negative pathogens …

Background: Current medical center practice allows for the automatic conversion of all
piperacillin/tazobactam orders from intermittent to extended infusion (EI). Objective: To …

Piperacillin combined with tazobactam was tested at both a fixed ratio (8: 1) and fixed
tazobactam concentration (4 µg/ml) against 2,685 consecutively isolated gram-negative …

Purpose The aim of the study was to investigate the in vitro antiinfective effect of piperacillin-
tazobactam (PIP-TZB) combinations on Escherichia coli in simulations of free concentration …

Objectives To explore extracorporeal membrane oxygenation (ECMO)-related alterations of
the pharmacokinetics (PK) of piperacillin/tazobactam and determine an optimal dosage …

We investigated the pharmacokinetics of piperacillin and tazobactam in the extracellular
space fluid of inflamed soft tissues of six patients with diabetic foot infection using in vivo …

(1) Background: Piperacillin-tazobactam represents the first-line option for treating infections
caused by full-or multi-susceptible Enterobacterales and/or Pseudomonas aeruginosa in …

Hospital microbiology laboratories from 41 states participated in a bacterial antimicrobial
susceptibility study comparing in vitro results generated by the standardized disk diffusion …

The pharmacokinetics of piperacillin were studied in a total of 26 Caucasian normal male
volunteers. Single intramuscular doses of 0.5, 1.0, and 2.0 g were given to three groups …