Improved quantitation and reproducibility in multi-PET/CT lung studies by combining CT information

BF Holman, V Cuplov, L Millner, R Endozo, TM Maher… - EJNMMI physics, 2018 - Springer
Background Matched attenuation maps are vital for obtaining accurate and reproducible
kinetic and static parameter estimates from PET data. With increased interest in PET/CT …

The effect of respiratory induced density variations on non-TOF PET quantitation in the lung

BF Holman, V Cuplov, BF Hutton… - Physics in Medicine …, 2016 - iopscience.iop.org
Accurate PET quantitation requires a matched attenuation map. Obtaining matched CT
attenuation maps in the thorax is difficult due to the respiratory cycle which causes both …

Failure to account for density variation during respiration can significantly affect PET quantitation in the lung.

B Holman, V Cuplov, L Millner, B Hutton, A Groves… - 2015 - Soc Nuclear Med
1770 Objectives PET quantitation in the lung is affected by local density changes due to
respiration and hence needs accurate attenuation maps (AM) for attenuation correction (AC) …

Density variation during respiration affects PET quantitation in the lung

BF Holman, V Cuplov, O Bertolli… - 2015 IEEE Nuclear …, 2015 - ieeexplore.ieee.org
PET quantitation depends on the accuracy of the CT-derived attenuation correction map. In
the lung, respiration leads to both positional and density mismatches, causing PET …

Issues in quantification of registered respiratory gated PET/CT in the lung

V Cuplov, B Holman, B Hutton, A Groves, K Thielemans - 2015 - Soc Nuclear Med
537 Objectives Lung density changes during respiration which affects PET/CT quantification
in the lung. We investigate the relation between density changes measured in CT, FDG …

The importance of correction for tissue fraction effects in lung PET: preliminary findings

T Lambrou, AM Groves, K Erlandsson… - European journal of …, 2011 - Springer
Purpose It has recently been recognized that PET/CT may play a role in diffuse parenchymal
lung disease. However, interpretation can be confounded due to the variability in lung …

Respiratory motion correction in dynamic PET with a single attenuation Map

EC Emond, A Bousse, M Machado… - 2019 IEEE Nuclear …, 2019 - ieeexplore.ieee.org
In addition to static tracer uptake values used routinely in clinical facilities, PET imaging can
provide useful information on tracer kinetics via the use of dynamic acquisitions where a set …

Optimisation of the air fraction correction for lung PET/CT: addressing resolution mismatch

F Leek, C Anderson, AP Robinson, RM Moss, JC Porter… - EJNMMI physics, 2023 - Springer
Abstract Background Increased pulmonary 18 F-FDG metabolism in patients with idiopathic
pulmonary fibrosis, and other forms of diffuse parenchymal lung disease, can predict …

Quantization accuracy of short-duration respiratory-gated PET/CT acquisitions

J Daouk, P Bailly, ME Meyer - Physica Medica, 2015 - Elsevier
Purpose PET/CT acquisitions are affected by physiological motion, which lowers the
quantization accuracy. Respiratory-gated PET/CT methods require a long acquisition time …

Impact of CT attenuation correction method on quantitative respiratory‐correlated (4D) PET/CT imaging

MJ Nyflot, TC Lee, AM Alessio… - Medical …, 2015 - Wiley Online Library
Purpose: Respiratory‐correlated positron emission tomography (PET/CT) 4D PET/CT is
used to mitigate errors from respiratory motion; however, the optimal CT attenuation …