Osteoprotegerin is the strongest predictor for progression of arterial calcification in peritoneal dialysis patients

M Avila, C Mora, MC Prado, M Zavala… - American Journal of …, 2017 - karger.com
Background: Arterial calcification (AC) is frequent in patients with end stage renal disease
and is also considered a risk factor for later morbidity and mortality. However, long-term …

Osteoprotegerin/RANKL axis and progression of coronary artery calcification in hemodialysis patients

A Ozkok, Y Caliskan, T Sakaci, G Erten… - Clinical journal of the …, 2012 - journals.lww.com
Results Baseline and first-year serum osteoprotegerin levels were significantly higher in the
progressive than nonprogressive group (17.39±9.67 versus 12.90±6.59 pmol/L, P= 0.02; …

Osteocalcin and vascular calcification in hemodialysis patients: an observational cohort study

HKH Keryakos, NI Okaily, MAY Boulis… - International Urology and …, 2021 - Springer
Background Vascular calcification contributes to morbidity and mortality in patients with
ESRD on maintenance hemodialysis. Aims To study the relationship between osteocalcin …

Elevated osteoprotegerin is associated with all-cause mortality in CKD stage 4 and 5 patients in addition to vascular calcification

MK Sigrist, A Levin, L Er… - Nephrology Dialysis …, 2009 - academic.oup.com
Background. Cardiovascular disease is the leading cause of death in the chronic kidney
disease (CKD) population. The mechanisms of vascular damage are not fully understood …

Bone mineral density and vascular calcification

N Joki, H Hase, Y Imamura - Clinical Calcium, 2005 - europepmc.org
It is of interest that in the general population, low bone mass is associated with a higher
mortality rate due to atherosclerotic cardiovascular disease. In addition, the degree of aortic …

Diabetes mellitus modifies the association between chronic kidney disease–mineral and bone disorder biomarkers and aortic stiffness in peritoneal dialysis patients

HJ Huang, BG Hsu, CH Wang, JP Tsai, YH Chen… - Scientific Reports, 2024 - nature.com
This study aimed to investigate the relationship of four chronic kidney disease–mineral and
bone disorder (CKD–MBD) biomarkers, including intact parathyroid hormone (PTH) …

Combination of biomarkers of vascular calcification and sTWEAK to predict cardiovascular events in chronic kidney disease

M Bozic, N Méndez-Barbero, C Gutiérrez-Muñoz… - Atherosclerosis, 2018 - Elsevier
Background and aims Vascular calcification (VC) and atherosclerosis are associated with an
increased cardiovascular morbimortality in chronic kidney disease (CKD). Osteoprotegerin …

Coronary calcifications in end-stage renal disease patients: a new link between osteoprotegerin, diabetes and body mass index?

G Cianciolo, G La Manna, G Donati, E Persici… - Blood purification, 2010 - karger.com
The aim of the study was to assess the factors potentially involved in coronary artery
calcifications (CAC) in end-stage renal disease patients. 253 hemodialysis (HD) patients (92 …

Soluble osteopontin and vascular calcification in hemodialysis patients

K Nitta, T Ishizuka, S Horita, T Hayashi, A Ajiro… - Nephron, 2001 - karger.com
Background: Vascular calcification often occurs in patients with uremia. As osteopontin
(OPN) is not only involved in the physiological but also the pathological calcification of …

Osteoprotegerin and sclerostin in chronic kidney disease prior to dialysis: potential partners in vascular calcifications

M Morena, I Jaussent, AM Dupuy… - Nephrology Dialysis …, 2015 - academic.oup.com
Background Osteoprotegerin (OPG), sclerostin and DKK1 constitute opposite bone turnover
inhibitors, OPG inhibiting osteoclastogenesis while sclerostin and DKK1 exerting their …