The results of recent studies indicate that in healthy men and women aged beyond
approximately 65 years, the energy-producing pathways in skeletal muscle may combine …

Recent studies suggest that the cost of muscle contraction may be reduced in old age, which
could be an important mediator of age-related differences in muscle fatigue under some …

This review describes the reductions and limitations in skeletal muscle function associated
with the normal aging process. Specific attention has been given to changes in muscle …

This review examines current evidence for the existence of aging processes in skeletal
muscle fibers. Experimental data demonstrating changes with age in nerve-muscle …

Skeletal muscle is a highly malleable tissue which, in youth, can respond to altered patterns
of contractile activity with remarkable adaptations. Since a reduction in adaptive capacity is …

It is generally accepted that the muscles of aged individuals contract with less force, have
slower relaxation rates, and demonstrate a downward shift in their force-velocity …

The effects of increasing age on skeletal muscle fatigue and endurance were assessed in
22 healthy young (14 men and 8 women; mean age, 28±6 years) and 16 healthy old (8 men …

This review summarizes the recent studies to understand the mechanisms of sarcopenia of
aging. A decrease in mitochondrial and nuclear gene transcriptions in skeletal muscle is …

We examined the muscle fatigue characteristics in older men and women and determined
whether these were related to the size, strength, or quality of muscle. A total of 1,512 men …

The percentage of Americans over the age of 65 yr is growing and this trend has heightened
interest in aging research. In this review of human studies, comparisons, as a function of …