Innovative freeze-drying technique in the fabrication of dissolving microneedle patch: Enhancing transdermal drug delivery efficiency

T Su, Z Tang, J Hu, Y Zhu, T Shen - Drug Delivery and Translational …, 2024 - Springer
Microneedle patch (MNP) has become a hot research topic in the field of transdermal drug
delivery due to its ability to overcome the stratum corneum barrier. Among the various types …

Dissolving polymer microneedles for transdermal delivery of insulin

N Zhang, X Zhou, L Liu, L Zhao, H Xie… - Frontiers in …, 2021 - frontiersin.org
It's of great significance to develop insulin-loaded dissolving microneedles (MNs) which are
fabricated with various methods and materials for transdermal delivery of insulin to …

Dissolving microneedle rollers for rapid transdermal drug delivery

XP Zhang, BL Zhang, BZ Chen, ZQ Zhao… - Drug Delivery and …, 2022 - Springer
Dissolving microneedle patch (DMNP) is a minimally invasive and painless self-
administration device. However, due to skin deformation, it is difficult to apply it on the large …

Dissolving microneedles for transdermal drug delivery: Advances and challenges

K Ita - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Over the last number of years, a significant body of evidence has shown the benefit of using
dissolving microneedles (DMNs) for transdermal drug delivery. These devices are prepared …

A fabrication of whole-dissovable microneedles patch in larger area for transdermal drug delivery

L Bao, N Takama, B Kim - 2019 IEEE CPMT Symposium Japan …, 2019 - ieeexplore.ieee.org
Dissolvable microneedles (MNs) patch has been extensively developed as a new technique
for minimally invasive transdermal drug livery. Recently, there are increasing needs for …

Fabrication of carboxymethylcellulose-gelatin dissolving microneedle patch for pain-free, efficient, and controlled transdermal delivery of insulin

BA Jana, RA Osmani, S Jaiswal, R Banerjee… - Journal of …, 2023 - Springer
Purpose Dissolving microneedle patches are attracting attention as they are associated with
improved patient compliance and safety. Methods This study fabricated dissolving …

Microneedles with tunable dissolution rate

H Kathuria, D Lim, J Cai, BG Chung… - … Biomaterials Science & …, 2020 - ACS Publications
Dissolvable microneedle (MN) patches have been widely investigated for transdermal drug
delivery. The dissolution rate of MN controls the status of drug release from the MN, which in …

Micro-pillar integrated dissolving microneedles for enhanced transdermal drug delivery

S Lee, S Fakhraei Lahiji, J Jang, M Jang, H Jung - Pharmaceutics, 2019 - mdpi.com
The dissolving microneedle (DMN) patch is a transdermal delivery system, containing arrays
of micro-sized polymeric needles capable of encapsulating therapeutic drugs within their …

Practicality of non-invasive glucagon-loaded dissolving microneedle for life-saving treatment of severe hypoglycemia in a diabetic rat model

X Wang, Y Ma, X Qi, X Ruan, D Cao, F Zhao - International Journal of …, 2023 - Elsevier
The development of dissolving microneedles (DMNs) has brought light to the transdermal
delivery of biomolecules that are released into the skin through the rapid dissolution of the …

Production of dissolvable microneedles using an atomised spray process: Effect of microneedle composition on skin penetration

MG McGrath, S Vucen, A Vrdoljak, A Kelly… - European Journal of …, 2014 - Elsevier
Dissolvable microneedles offer an attractive delivery system for transdermal drug and
vaccine delivery. They are most commonly formed by filling a microneedle mold with liquid …