[HTML][HTML] Major oncogenic drivers and their clinicopathological correlations in sporadic childhood papillary thyroid carcinoma in Belarus

TI Rogounovitch, SV Mankovskaya, MV Fridman… - Cancers, 2021 - mdpi.com
Simple Summary Childhood papillary thyroid carcinomas (PTCs) detected after the
Chernobyl accident were genetically characterized by a high prevalence of gene …

Fusion oncogenes are the main genetic events found in sporadic papillary thyroid carcinomas from children

MICV Cordioli, L Moraes, AU Bastos, P Besson… - Thyroid, 2017 - liebertpub.com
Background: Previous studies reported significant differences in the clinical presentation
and outcomes of papillary thyroid carcinoma (PTC) in pediatric patients compared with …

Molecular pathogenesis of pediatric thyroid carcinoma

N Mitsutake, V Saenko - Journal of radiation research, 2021 - academic.oup.com
There has been little understanding of the molecular pathogenesis of pediatric thyroid
cancers. Most of them are histologically classified as papillary thyroid carcinoma (PTC) …

[HTML][HTML] Molecular alterations in relation to histopathological characteristics in a large series of pediatric papillary thyroid carcinoma from a single institution

E Macerola, A Proietti, AM Poma, C Ugolini… - Cancers, 2021 - mdpi.com
Simple Summary Papillary thyroid carcinoma (PTC) in pediatric patients shows different
characteristics compared with PTC in adults. In this large mono-institutional cohort of …

High Prevalence of RET/PTC Rearrangements in Ukrainian and Belarussian Post-Chernobyl Thyroid Papillary Carcinomas: A Strong Correlation between RET …

GA Thomas, H Bunnell, HA Cook… - The Journal of …, 1999 - academic.oup.com
A sharp increase in the incidence of pediatric thyroid papillary cancer was documented after
the Chernobyl power plant explosion. An increased prevalence of rearrangements of the …

Molecular genetics of childhood papillary thyroid carcinomas after irradiation: high prevalence of RET rearrangement

HM Rabes, S Klugbauer - Genes and Environment in Cancer, 1998 - Springer
Epidemiological studies have revealed a connection between thyroid carcinogenesis and a
history of radiation. The molecular mechanisms involed are not well understood. It has been …

Solid variant of papillary thyroid carcinoma: an under-recognized entity

R Ohashi - Endocrine journal, 2020 - jstage.jst.go.jp
Solid variant of papillary thyroid carcinoma (SVPTC) is a rare morphological variant of
papillary thyroid carcinoma (PTC). SVPTC is histologically characterized by predominant …

Distinct Pattern of ret Oncogene Rearrangements in Morphological Variants of Radiation-induced and Sporadic Thyroid Papillary Carcinomas in Children

YE Nikiforov, JM Rowland, KE Bove… - Cancer Research, 1997 - AACR
In this study, we compare the morphological and genetic characteristics of 38 post-
Chernobyl thyroid papillary carcinomas from Belarussian children 5–18 years old with those …

Classic architecture with multicentricity and local recurrence, and absence of TERT promoter mutations are correlates of BRAF V600E harboring pediatric papillary …

S Onder, S Ozturk Sari, G Yegen, IC Sormaz… - Endocrine …, 2016 - Springer
This study is aimed to investigate the BRAF V600E and TERT promoter mutation profile of
50 pediatric papillary thyroid carcinomas (PTCs) to refine their clinicopathological correlates …

Oncogenic alterations in papillary thyroid cancers of young patients

G Sassolas, Z Hafdi-Nejjari, A Ferraro… - Thyroid, 2012 - liebertpub.com
Background: Papillary thyroid carcinoma (PTC) in young people usually has an aggressive
initial presentation, though a good general prognosis despite recurrences in 10%–20% of …