We evaluated neutrophil activation by measuring its phagocytic ability and oxidative burst
activity in 16 patients with sepsis and 16 healthy volunteers. We also focused on neutrophil …

Severe septic syndromes deeply impair innate and adaptive immunity and are responsible
for sepsis-induced immunosuppression. Although neutrophils represent the first line of …

Sepsis is a condition of severe organ failure caused by the maladaptive response of the host
to an infection. It is a severe complication affecting critically ill patients, which can progress …

Objective: Sepsis is defined as life-threatening organ dysfunction due to a dysregulated host
response to infection. In this article, we reviewed the correlation between neutrophil …

Background The nature of the inflammatory response underscoring the pathophysiology of
sepsis has been extensively studied. We hypothesized that different cell functions would be …

Patients with sepsis commonly develop leukocytosis, which is presumed to reflect a host
response to infection. Effective phagocytosis by neutrophils is crucial in the clearance of …

Neutrophils play a key role in the pathophysiology of septic multiple organ dysfunction
syndrome (MODS) through excessive release of toxic granule components and reactive …

Sepsis is a prevalent disease that has alarmingly high mortality rates and, for several
survivors, long-term morbidity. The modern definition of sepsis is an aberrant host response …

In this study, our aims were to evaluate the reactive oxygen species (ROS) and nitric oxide
(NO) generation by monocytes and neutrophils from septic patients and to correlate their …

Background. Neutrophil dysfunction in sepsis has been implicated in the pathogenesis of
multiorgan failure; however, the role of neutrophil extracellular traps (NETs) remains …