Mechanism of Constitutive Export from the Golgi: Bulk Flow via the Formation, Protrusion, and En Bloc Cleavage of large trans-Golgi Network Tubular Domains

EV Polishchuk, A Di Pentima, A Luini… - Molecular biology of …, 2003 - Am Soc Cell Biol
Transport of constitutive cargo proteins from the Golgi complex to the plasma membrane
(PM) is known to be mediated by large tubular-saccular carriers moving along microtubules …

Morphogenesis of post-Golgi transport carriers

A Luini, AA Mironov, EV Polishchuk… - Histochemistry and cell …, 2008 - Springer
The trans-Golgi network (TGN) is one of the main, if not the main, sorting stations in the
process of intracellular protein trafficking. It is therefore of central importance to understand …

The GRIP Domain is a Specific Targeting Sequence for a Population of trans‐Golgi Network Derived Tubulo‐Vesicular Carriers

DL Brown, K Heimann, J Lock, L Kjer‐Nielsen… - Traffic, 2001 - Wiley Online Library
Vesicular carriers for intracellular transport associate with unique sets of accessory
molecules that dictate budding and docking on specific membrane domains. Although many …

The formation of TGN-to-plasma-membrane transport carriers

F Bard, V Malhotra - Annu. Rev. Cell Dev. Biol., 2006 - annualreviews.org
In the trans-Golgi network (TGN), proteins are sorted for transport to the endosomes, plasma
membrane, preceding Golgi cisternae, and endoplasmic reticulum. The formation of clathrin …

Dual-color visualization of trans-Golgi network to plasma membrane traffic along microtubules in living cells

D Toomre, P Keller, JWJC Olivo… - Journal of cell …, 1999 - journals.biologists.com
The mechanisms and carriers responsible for exocytic protein trafficking between the trans-
Golgi network (TGN) and the plasma membrane remain unclear. To investigate the …

Regulation of cargo export and sorting at the trans‐Golgi network

R Di Martino, L Sticco, A Luini - FEBS letters, 2019 - Wiley Online Library
The sorting and distribution to different final destinations of roughly a third of the membrane
and secreted proteins occurs at the level of the trans‐Golgi network (TGN). This TGN …

The golgin coiled-coil proteins capture different types of transport carriers via distinct N-terminal motifs

M Wong, AK Gillingham, S Munro - BMC biology, 2017 - Springer
Background The internal organization of cells depends on mechanisms to ensure that
transport carriers, such as vesicles, fuse only with the correct destination organelle. Several …

Kinetic analysis of secretory protein traffic and characterization of Golgi to plasma membrane transport intermediates in living cells

K Hirschberg, CM Miller, J Ellenberg… - The Journal of cell …, 1998 - rupress.org
Quantitative time-lapse imaging data of single cells expressing the transmembrane protein,
vesicular stomatitis virus ts045 G protein fused to green fluorescent protein (VSVG–GFP) …

Sending out molecules from the TGN

BR Ramazanov, ML Tran, J von Blume - Current opinion in cell biology, 2021 - Elsevier
The sorting of secreted cargo proteins and their export from the trans-Golgi network (TGN)
remains an enigma in the field of membrane trafficking; although the sorting mechanisms of …

The regulation of endosome‐to‐Golgi retrograde transport by tethers and scaffolds

PZC Chia, PA Gleeson - Traffic, 2011 - Wiley Online Library
Retrograde transport between endosomes and the trans‐Golgi network (TGN) is essential
for the recycling of membrane proteins which are involved in a range of biological …