Oxidative stress and inducible nitric oxide synthase induction in carcinogenesis
F Farinati, M Piciocchi, E Lavezzo, M Bortolami… - Digestive …, 2010 - karger.com
Background: Chronic inflammation is linked to an increased risk of cancer. The molecular
mechanisms underlying this correlation have been long investigated and it is well known …
mechanisms underlying this correlation have been long investigated and it is well known …
Inducible nitric oxide synthase in the carcinogenesis of gastrointestinal cancers
Significance: Gastrointestinal (GI) cancer taken together constitutes one of the most common
cancers worldwide with a broad range of etiological mechanisms. In this review, we have …
cancers worldwide with a broad range of etiological mechanisms. In this review, we have …
Nitric oxide in gastrointestinal epithelial cell carcinogenesis: linking inflammation to oncogenesis
M Jaiswal, NF LaRusso… - American Journal of …, 2001 - journals.physiology.org
Chronic inflammation of gastrointestinal tissues is a well-recognized risk factor for the
development of epithelial cell-derived malignancies. Although the inflammatory mediators …
development of epithelial cell-derived malignancies. Although the inflammatory mediators …
Potential biomarkers associated with oxidative stress for risk assessment of colorectal cancer
P Mandal - Naunyn-Schmiedeberg's archives of pharmacology, 2017 - Springer
Cells are continuously threatened by the damage caused by reactive oxygen/nitrogen
species (ROS/RNS), which are produced during physiological oxygen metabolism. In our …
species (ROS/RNS), which are produced during physiological oxygen metabolism. In our …
chronic inflammation and reactive oxygen and nitrogen metabolism–implications in DNA damage and mutagenesis
MB Grisham, D Jourd'Heuil… - … & Therapeutics: Nitric …, 2000 - Wiley Online Library
It is well known that chronic inflammation of the digestive tract is associated with an
increased risk of malignant transformation. Because phagocytic leukocytes and cytokine …
increased risk of malignant transformation. Because phagocytic leukocytes and cytokine …
Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis
S Kawanishi, Y Hiraku, S Pinlaor, N Ma - 2006 - degruyter.com
Infection and chronic inflammation are proposed to contribute to carcinogenesis through
inflammation-related mechanisms. Infection with hepatitis C virus, Helicobacter pylori and …
inflammation-related mechanisms. Infection with hepatitis C virus, Helicobacter pylori and …
Oxidative stress in inflammation‐based gastrointestinal tract diseases: Challenges and opportunities
YJ Kim, EH Kim, KB Hahm - Journal of gastroenterology and …, 2012 - Wiley Online Library
Oxygen free radicals in excessively high amounts are all very reactive chemically and can
impose a detrimental influence on living organisms by provoking “oxidative stress” that can …
impose a detrimental influence on living organisms by provoking “oxidative stress” that can …
Oxidative stress in ulcerative colitis-associated carcinogenesis
A Roessner, D Kuester, P Malfertheiner… - … -Research and practice, 2008 - Elsevier
Oxidative stress is defined as an imbalance between generation of reactive oxygen species
(ROS) and decreased antioxidant defense systems. Oxidative stress develops particularly in …
(ROS) and decreased antioxidant defense systems. Oxidative stress develops particularly in …
Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis
H Ohshima, H Bartsch - Mutation Research/Fundamental and Molecular …, 1994 - Elsevier
Infection by bacteria, parasites or viruses and tissue inflammation such as gastritis, hepatitis
and colitis are recognized risk factors for human cancers at various sites. Nitric oxide (NO) …
and colitis are recognized risk factors for human cancers at various sites. Nitric oxide (NO) …
Nitric oxide signaling in colon cancer chemoprevention
CV Rao - … Research/Fundamental and Molecular Mechanisms of …, 2004 - Elsevier
Nitric oxide (NO) is a pleiotrophic regulator, pivotal to numerous biological processes,
including vasodilation, neurotransmission, and macrophage-mediated immunity. The highly …
including vasodilation, neurotransmission, and macrophage-mediated immunity. The highly …