Galanin–25 years with a multitalented neuropeptide: Galanin and the neuroendocrine axes

I Mechenthaler - Cellular and Molecular Life Sciences, 2008 - Springer
Galanin has diverse physiological functions, including nociception, arousal/sleep regulation,
cognition, and many aspects of neuroendocrine activities that are associated with feeding …

Galanin–25 years with a multitalented neuropeptide: Galanin and addiction

MR Picciotto - Cellular and Molecular Life Sciences, 2008 - Springer
There has been increasing interest in the ability of neuropeptides involved in feeding to
modulate circuits important for responses to drugs of abuse. A number of peptides with …

Effect of galanin on food intake in rats: involvement of lateral and ventromedial hypothalamic sites

RR Schick, S Samsami… - American Journal …, 1993 - journals.physiology.org
Galanin has previously been reported to elicit feeding in satiated animals when injected into
the hypothalamic paraventricular nucleus. It is not known, however, 1) whether this action is …

Human galanin: molecular cloning reveals a unique structure

HF Evans, J Shine - Endocrinology, 1991 - academic.oup.com
Galanin, a novel neuropeptide/hypothalamic hormone originally identified and isolated by
virtue of its carboxyterminal amide group, has recently been shown to have a diverse range …

Linear and cyclic N‐terminal galanin fragments and analogs as ligands at the hypothalamic galanin receptor

TUT Land, OLO Langel, M LÖW… - … journal of peptide …, 1991 - Wiley Online Library
The neuropeptide galanin (1–29) binds with high affinity to hypothalamic receptors (KD∼
0.9 nM) and regulates feeding behavior. The N‐terminal fragments (1–16),(1–16) NH2 are …

Phenotypic analysis of mice deficient in the type 2 galanin receptor (GALR2)

ML Gottsch, H Zeng, JG Hohmann… - … and Cellular Biology, 2005 - Taylor & Francis
Galanin is a neuropeptide implicated in the regulation of feeding, reproduction, cognition,
nociception, and seizure susceptibility. There are three known galanin receptor (GALR) …

Obesity and endocrine dysfunction in mice with deletions of both neuropeptide Y and galanin

JG Hohmann, DN Teklemichael… - … and cellular biology, 2004 - Taylor & Francis
Neuropeptide Y (NPY) and galanin have both been implicated in the regulation of body
weight, yet mice bearing deletions of either of these molecules have unremarkable …

The role of galanin in metabolic disorders leading to type 2 diabetes mellitus.

IN Legakis - Drug News & Perspectives, 2005 - europepmc.org
A large number of neurotransmitters have been identified that influence food intake when
administered directly into the central nervous system of experimental animals. In some …

Pharmacological and biochemical characterization of a recombinant human galanin GALR1 receptor: agonist character of chimeric galanin peptides

LW Fitzgerald, JP Patterson, DS Conklin… - … of Pharmacology and …, 1998 - ASPET
The galanin neuropeptide system is widely distributed throughout the brain and periphery
and is thought to play a role in feeding, pain and reproduction. To evaluate the human …

Galanin and the neuroendocrine axes

I Merchenthaler - Galanin, 2010 - Springer
Galanin has diverse physiological functions, including nociception, arousal/sleep regulation,
cognition, and many aspects of neuroendocrine activities that are associated with feeding …