Galanin antagonist increases insulin resistance by reducing glucose transporter 4 effect in adipocytes of rats

L Guo, M Shi, L Zhang, G Li, L Zhang, H Shao… - General and …, 2011 - Elsevier
Seeing that galanin increases animal body weight on the conditions of inhibiting insulin
secretion and animals with metabolic disorder of galanin easily suffer from diabetes, we …

Regional stimulatory and inhibitory effects of guanine nucleotides on [125I] galanin binding in rat brain: relationship with the rate of occupancy of galanin receptors by …

I Lagny-Pourmir, J Epelbaum - Neuroscience, 1992 - Elsevier
Galanin has been shown to stimulate feeding or modulate neuroendocrine secretions when
administered centrally. In the present work, using quantitative autoradiography, we …

Activity of centrally administered galanin fragments on stimulation of feeding behavior and on galanin receptor binding in the rat hypothalamus

JN Crawley, MC Austin, SM Fiske, B Martin… - Journal of …, 1990 - Soc Neuroscience
Synthetic fragments of galanin 1–29 were administered intraventricularly or into the
paraventricular nucleus of the hypothalamus for analysis of the critical amino acid sequence …

Differential patterns of Fos induction in the hypothalamus of the rat following central injections of galanin-like peptide and galanin

GS Fraley, I Shimada, JW Baumgartner… - …, 2003 - academic.oup.com
Galanin and its newly discovered relative galanin-like peptide (GALP) are neuropeptides
that are implicated in the neuroendocrine regulation of body weight and reproduction. GALP …

Galanin in the PVN increases nutrient intake and changes peripheral hormone levels in the rat

SE Kyrkouli, JH Strubbe, AJW Scheurink - Physiology & behavior, 2006 - Elsevier
In self-selection feeding paradigms, rats display differential patterns of nutrient (protein,
carbohydrate or fat) intake. Factors known to influence this selection include brain peptides …

Galanin receptor-mediated inhibition of glutamate release in the arcuate nucleus of the hypothalamus

GA Kinney, PJ Emmerson, RJ Miller - Journal of Neuroscience, 1998 - Soc Neuroscience
It is thought that galanin, a 29 amino acid neuropeptide, is involved in various neuronal
functions, including the regulation of food intake and hormone release. Consistent with this …

Galanin peptide family regulation of glucose metabolism

P Fang, M Yu, M Shi, P Bo, Z Zhang - Frontiers in Neuroendocrinology, 2020 - Elsevier
Recent preclinical and clinical studies have indicated that the galanin peptide family may
regulate glucose metabolism and alleviate insulin resistance, which diminishes the …

Galanin and consummatory behavior: special relationship with dietary fat, alcohol and circulating lipids

JR Barson, I Morganstern, SF Leibowitz - Galanin, 2010 - Springer
Galanin (GAL) plays an integral role in consummatory behavior. In particular, hypothalamic
GAL has a positive, reciprocal relationship with dietary fat and alcohol. In this relationship …

Galanin in the hypothalamus of fed and fasted lean and obese Zucker rats

B Beck, A Burlet, JP Nicolas, C Burlet - Brain research, 1993 - Elsevier
Abstract Galanin (GAL), a 29 aminoacid peptide, is widely distributed in the central nervous
system and especially in the hypothalamus. It strongly stimulates food intake when it is …

Galanin—10 years with a neuroendocrine peptide

K Bedecs, M Berthold, T Bartfai - The international journal of biochemistry & …, 1995 - Elsevier
Galanin is a 29 30 amino acids long neuropeptide which does not belong to any known
peptide family. The N-terminal first 16 amino acids of the molecule are both necessary and …