[HTML][HTML] Preoperative identification of low-risk medullary thyroid carcinoma: potential application to reduce total thyroidectomy

H Park, HJ Ryu, J Heo, MK Chung, YI Son, JH Kim… - Scientific Reports, 2023 - nature.com
Current guidelines recommend total thyroidectomy with central lymph node dissection
(CND) for patients with medullary thyroid carcinoma (MTC). This study aimed to identify low …

Prophylactic lateral neck dissection for medullary thyroid carcinoma is not associated with improved survival

PM Spanheimer, I Ganly, JF Chou, M Capanu… - Annals of surgical …, 2021 - Springer
Background Patients with medullary thyroid carcinoma (MTC) often receive lateral lymph
node dissection with total thyroidectomy when calcitonin levels are elevated, even in the …

A comparison of outcomes in medullary thyroid carcinoma patients with and without a preoperative diagnosis: A multicenter retrospective cohort study

K Oleinikov, E Yaakov, A Mizrachi, D Hirsch… - Thyroid, 2023 - liebertpub.com
Background: Cytological limitations pose a challenge to preoperative diagnosis of medullary
thyroid carcinoma (MTC) and therefore, a significant subset of patients is only diagnosed …

Lymph node metastases and elevated postoperative calcitonin: predictors of poor survival in medullary thyroid carcinoma

P Siironen, J Hagström, HO Mäenpää, J Louhimo… - Acta …, 2016 - Taylor & Francis
Background Total thyroidectomy is the treatment of choice for medullary thyroid carcinoma
(MTC), but the extent of neck dissection is controversial. Lymph node metastases, distant …

Survival in patients with medullary thyroid cancer after less than the recommended initial operation

RW Randle, MF Bates, DF Schneider… - Journal of surgical …, 2018 - Wiley Online Library
Background and Objectives We aimed to evaluate the disease specific‐survival (DSS) of
patients with Medullary Thyroid Cancer (MTC) confined to the central neck based on the …

Does the extent of neck surgery based on preoperative calcitonin level influence survival in medullary thyroid carcinoma: a retrospective tertiary centre experience

W Ansley, A Kamyab, L Noden… - The Annals of The …, 2024 - publishing.rcseng.ac.uk
Introduction Medullary thyroid carcinoma (MTC) is a rare thyroid cancer arising from the
calcitonin-secreting parafollicular cells. Previous studies suggested a preoperative …

The effect of extent of surgery and number of lymph node metastases on overall survival in patients with medullary thyroid cancer

NH Esfandiari, DT Hughes, H Yin… - The Journal of …, 2014 - academic.oup.com
Context: Total thyroidectomy with central lymph node dissection is recommended in patients
with medullary thyroid cancer (MTC). However, the relationship between disease severity …

Extension of prophylactic surgery in medullary thyroid carcinoma. Differences between sporadic and hereditary tumours according to calcitonin levels and lymph node …

LD Juez, E Mercader, I Amunategui… - World journal of …, 2022 - Wiley Online Library
Introduction Currently, there is no consensus on the indication of prophylactic surgery of the
nodal compartments in the treatment of medullary thyroid carcinoma (MTC). The aim of our …

Calcitonin secretory index and unsuspected nodal disease in medullary thyroid carcinoma

S Filimon, RJ Payne, MJ Black, MP Hier, AM Mlynarek… - Endocrine Practice, 2018 - Elsevier
Objective: Medullary thyroid carcinoma (MTC) is a rare thyroid malignancy originating from
parafollicular C-cells with the potential for aggressive behavior. The extent of lymph node …

Prognostic variables affecting primary treatment outcome for medullary thyroid cancer

S Momin, D Chute, B Burkey, J Scharpf - Endocrine Practice, 2017 - Elsevier
Objective: Identifying prognostic risk factors and determining the efficacy of common surgical
treatments is critical to determine optimal treatment strategies for patients with medullary …