Epidemiological and experimental evidence support a role for sex steroid hormones in
colorectal cancer. The aims of this study were to determine expression of oestrogen receptor …

Sex differences exist in the site specific incidences of colorectal cancer. The increased
incidence of colonic cancer in women with breast cancer and the protective effect of …

In recent years, several lines of epidemiologic, clinical and experimental evidences have
been reported showing that estrogen hormones may be involved in malignant colorectal …

Knowledge regarding the expression of the recently cloned estrogen receptor β (ERβ) in
colonic mucosa is limited. In this study, we demonstrated that five human colon cancer cell …

Methods ER and PR expression in cytoplasm and nucleus of tumor tissues and normal
mucosas from 45 colorectal cancer patients were quantitatively measured using radioligand …

Twenty-four colorectal carcinomas were assayed for estrogen and progestin receptors by
sucrose gradient centrifugation. Most biopsies were either completely estrogen receptor …

Tumors from patients with primary colon cancer were studied for the presence of steroid
hormone receptors for estrogen (E2), progesterone (Prog), dihydrotestosterone (DHT) and …

Androgen, progesterone and estrogen receptors were analyzed in 12 primary colonic
cancers and 16 primary rectal cancers. Androgen and progesterone receptors were positive …

Cancerous tissue from 86 patients with primary gastric cancer were examined for the
presence of receptors for estrogen (ER) and progesterone (PgR). ER and PgR were present …

Epidemiological data suggest a protective effect for estrogen replacement therapy on colon
cancer. The estrogen receptor (ER) is required for the action of estrogen. The ER-β isoform …