Unraveling the complexities of the interferon response during SARS-CoV infection
A De Lang, T Baas, SL Smits, MG Katze… - Future …, 2009 - Taylor & Francis
Viruses employ different strategies to circumvent the antiviral actions of the innate immune
response. SARS coronavirus (SARS-CoV), a virus that causes severe lung damage …
response. SARS coronavirus (SARS-CoV), a virus that causes severe lung damage …
Interferon interplay helps tissue cells to cope with SARS-coronavirus infection
T Kuri, F Weber - Virulence, 2010 - Taylor & Francis
SARS coronavirus (SARS-CoV), the causative agent of severe acute respiratory syndrome,
is a versatile pathogen armed with a host of factors countering the antiviral type I interferon …
is a versatile pathogen armed with a host of factors countering the antiviral type I interferon …
Interferon priming enables cells to partially overturn the SARS coronavirus-induced block in innate immune activation
T Kuri, X Zhang, M Habjan… - Journal of general …, 2009 - microbiologyresearch.org
SARS coronavirus (SARS-CoV) is known to efficiently suppress the induction of antiviral
type I interferons (IFN-α/β) in non-lymphatic cells through inhibition of the transcription factor …
type I interferons (IFN-α/β) in non-lymphatic cells through inhibition of the transcription factor …
Interferon and cytokine responses to SARS-coronavirus infection
V Thiel, F Weber - Cytokine & growth factor reviews, 2008 - Elsevier
The sudden emergence of severe acute respiratory syndrome (SARS) has boosted research
on innate immune responses to coronaviruses. It is now well established that the causative …
on innate immune responses to coronaviruses. It is now well established that the causative …
Functional genomics highlights differential induction of antiviral pathways in the lungs of SARS-CoV–infected macaques
A De Lang, T Baas, T Teal, LM Leijten, B Rain… - PLoS …, 2007 - journals.plos.org
The pathogenesis of severe acute respiratory syndrome coronavirus (SARS-CoV) is likely
mediated by disproportional immune responses and the ability of the virus to circumvent …
mediated by disproportional immune responses and the ability of the virus to circumvent …
Autocrine interferon priming in macrophages but not dendritic cells results in enhanced cytokine and chemokine production after coronavirus infection
H Zhou, J Zhao, S Perlman - MBio, 2010 - Am Soc Microbiol
Coronaviruses efficiently inhibit interferon (IFN) induction in nonhematopoietic cells and
conventional dendritic cells (cDC). However, IFN is produced in infected macrophages …
conventional dendritic cells (cDC). However, IFN is produced in infected macrophages …
SARS coronavirus pathogenesis: host innate immune responses and viral antagonism of interferon
AL Totura, RS Baric - Current opinion in virology, 2012 - Elsevier
SARS-CoV is a pathogenic coronavirus that emerged from a zoonotic reservoir, leading to
global dissemination of the virus. The association SARS-CoV with aberrant cytokine …
global dissemination of the virus. The association SARS-CoV with aberrant cytokine …
[HTML][HTML] Early gene expression events in ferrets in response to SARS coronavirus infection versus direct interferon-alpha2b stimulation
A Danesh, CM Cameron, AJ León, L Ran, L Xu, Y Fang… - Virology, 2011 - Elsevier
Type I interferons (IFNs) are essential to the clearance of viral diseases, however, a clear
distinction between genes upregulated by direct virus–cell interactions and genes …
distinction between genes upregulated by direct virus–cell interactions and genes …
Severe acute respiratory syndrome and the innate immune responses: modulation of effector cell function without productive infection
CTK Tseng, LA Perrone, H Zhu, S Makino… - The Journal of …, 2005 - journals.aai.org
Severe acute respiratory syndrome (SARS) caused by a novel human coronavirus (CoV),
designated SARS-CoV, is a highly contagious respiratory disease with the lungs as a major …
designated SARS-CoV, is a highly contagious respiratory disease with the lungs as a major …
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