The author presents his experience with the thyroid complications of amiodarone therapy:
exceptional but sometimes serious conditions. Both, hypo-and hyperthyroidism can occur …

Amiodarone has been used in cardiology for more than 20 years as an anti-angina and anti-
arrhythmia agent. In the seventies, variations in thyroid hormone and TSH concentrations …

Of a population of 400 patients treated with amiodarone, 97 underwent thyroid function
evaluation. Of these, 20 patients proved to be thyrotoxic and 16 hypothyroid. In thyrotoxic …

Amiodarone is a potent antiarrhythmic drug associated with thyroid dysfunction. Its high
iodine content causes inhibition of 5'-deiodinase activity. Most patients remain euthyroid …

Amiodarone has been reported as an anti-anginal drug in 19h7 [11 and as an anti-
arrhythmic drug in 1969 [2]. Thyroid side-effects (hypothyroidism and thyrotoxicosis) were …

Amiodarone, an iodinated benzofuran derivative, was introduced in the 1960s as an
antianginal agent with coronary vasodilator properties. Later description of its antiaiThythmic …

Amiodarone-induced thyrotoxicosis: a difficult diagnostic and therapeutic challenge* Page 1
Clinical Endocrinology (2002) 56, 23–24 © 2002 Blackwell Science Ltd 23 Blackwell Science …

Amiodarone blocks the action of thyroid hormone by the inhibition of 5′-deiodinase which
reduces production of T 3 in peripheral tissues and possibly by blocking nuclear binding of T …

Cases of hypothyroidism and hyperthyroidism associated with amiodarone therapy are
described, and the mechanisms, clinical appearance, and management of amiodarone …

Thyroid function was evaluated clinically and biochemically in 12 patients with ischaemic
heart disease receiving 200 mg oral amiodarone three times daily for periods up to 6 weeks …