Bacteria are key initiating factors in the development of chronic intestinal inflammation that
characterizes the idiopathic inflammatory bowel diseases (IBDs), ulcerative colitis (UC) and …

The prokaryotic and eukaryotic cells of the colon exist in a highly complex, but harmonious
relationship. Disturbances in this remarkable symbiosis can result in the development of …

Most conventional forms of drug therapy suppress or modify the host immunoinflammatory
response and neglect the other contributor to disease pathogenesis—the environmental …

Inflammatory bowel disease (IBD) is a chronic relapsing disorder involving a dysregulated
host–microbiota interaction. IBD patients have been shown to possess an increased risk for …

Crohn's disease and ulcerative colitis are the two principal forms of inflammatory bowel
disease (IBD). The root causes of these chronic and acute immunological disorders are …

A complex set of interactions between the human genes encoding innate protective
functions and immune defenses and the environment of the intestinal mucosa with its …

Inflammatory bowel disease (IBD) consists of two distinct clinical forms, ulcerative colitis
(UC) and Crohn's disease (CD), with unknown aetiology, which nevertheless are considered …

The intestinal microflora is a large bacterial community that colonizes the gut, with a
metabolic activity equal to an organ and various functions that affect the physiology and …

The normal colonic microflora is intimately involved in the aetiology of inflammatory bowel
diseases (IBD) such as ulcerative colitis (UC) and Crohn's disease (CD). These conditions …

Understanding the mechanisms responsible for the beneficial effect of probiotics in
inflammatory bowel disease and experimental colitis may help understand the role of …