Antigen specific immunotherapy aims to tolerise patients to specific autoantigens that are
responsible for the pathology of an autoimmune disease. Immune tolerance is generated in …

Gold nanoparticle (AuNP) bioconjugates have been used as therapeutic and diagnostic
tools; however, in vivo biocompatibility and cytotoxicity continue to be two fundamental …

Coating gold nanoparticle surfaces with peptide molecules will expand the application
potentialities of these nanomaterials in biomedical sciences. Our studies investigated some …

Gold nanoparticles (AuNPs) are a type of widely used nanomaterials with unique chemical
and physical properties. AuNPs can be readily synthesized, and modified with various …

Immune responses are involved in the pathogenesis of many diseases, including cancer,
autoimmune diseases, and chronic inflammation. These responses are attributed to immune …

We report on a systematic investigation of molecular conjugation of tumor necrosis factor-α
(TNF) protein onto gold nanoparticles (AuNPs) and the subsequent binding behavior to its …

In the present study, surface-modified nanoparticles based on biodegradable material were
used for antibody coupling in order to get a selective drug carrier systems. Gelatin …

Targeted metallic nanoparticles have shown promise as contrast agents for molecular
imaging. To obtain molecular specificity, the nanoparticle surface must be appropriately …

In this paper, we report a novel approach using peptide CALNN and its derivative
CALNNGGRRRRRRRR (CALNNR8) to functionalize gold nanoparticles for intracellular …

Pegylation of gold nanoshells provides an effective means to reduce their
reticuloendothelial system (RES) clearance in body. In this study, we perform a parametric …