Multivalent gold nanoparticle–peptide conjugates for targeting intracellular bacterial infections

R Chowdhury, H Ilyas, A Ghosh, H Ali, A Ghorai… - Nanoscale, 2017 - pubs.rsc.org
Although nanoparticle-tagged antimicrobal peptides have gained considerable importance
in recent years, their structure–function correlation has not yet been explored. Here, we have …

[HTML][HTML] Enhanced intracellular translocation and biodistribution of gold nanoparticles functionalized with a cell-penetrating peptide (VG-21) from vesicular stomatitis …

PM Tiwari, E Eroglu, SS Bawage, K Vig, ME Miller… - Biomaterials, 2014 - Elsevier
Reduced toxicity and ease of modification make gold nanoparticles (GNPs) suitable for
targeted delivery, bioimaging and theranostics by conjugating cell-penetrating peptides …

Transdermal gene delivery by functional peptide-conjugated cationic gold nanoparticle reverses the progression and metastasis of cutaneous melanoma

J Niu, Y Chu, YF Huang, YS Chong… - … applied materials & …, 2017 - ACS Publications
Permeability barrier imposed by stratum corneum makes an extreme challenge for the
topical delivery of plasmid DNA (pDNA), which is widely used in gene therapy. Existing …

Polymer conjugated gold nanoparticles in biomedical applications

S Anniebell, SCB Gopinath - Current medicinal chemistry, 2018 - ingentaconnect.com
Background: Research interest on the properties of polymer conjugated gold nanoparticle
(GNP) in biomedicine is rapidly rising because of the extensive evidences for their unique …

Synthesis of patient-specific nanomaterials

J Lazarovits, YY Chen, F Song, W Ngo, AJ Tavares… - Nano …, 2018 - ACS Publications
Nanoparticles are engineered from materials such as metals, polymers, and different carbon
allotropes that do not exist within the body. Exposure to these exogenous compounds raises …

Interactions of cationic gold nanoclusters with serum proteins and effects on their cellular responses

M Wen, Y Li, W Zhong, Q Li, L Cao, L Tan… - Journal of Colloid and …, 2022 - Elsevier
Cationic nanoparticles (NPs) have shown great potential in biological applications owing to
their distinct features such as favorable cellular internalization and easy binding to …

One-Pot Synthesis of Polypeptide–Gold Nanoconjugates for in Vitro Gene Transfection

X Yan, J Blacklock, J Li, H Möhwald - Acs Nano, 2012 - ACS Publications
We present a general strategy to create polypeptide–gold nanoconjugates by a one-pot
synthesis approach, where polypeptides act not only as capping agents but also as …

Interleukin-10 conjugation to carboxylated PVP-coated silver nanoparticles for improved stability and therapeutic efficacy

DR Baganizi, E Nyairo, SA Duncan, SR Singh… - Nanomaterials, 2017 - mdpi.com
Interleukin-10 (IL-10) is a key anti-inflammatory and immunosuppressive cytokine and
therefore represents a potential therapeutic agent especially in inflammatory diseases …

Combating complement's deleterious effects on nanomedicine by conjugating complement regulatory proteins to nanoparticles

Z Wang, ED Hood, J Nong, J Ding… - Advanced …, 2022 - Wiley Online Library
Complement opsonization is among the biggest challenges facing nanomedicine. Nearly
instantly after injection into blood, nanoparticles are opsonized by the complement protein …

Size-dependent anti-inflammatory activity of a peptide-gold nanoparticle hybrid in vitro and in a mouse model of acute lung injury

W Gao, Y Wang, Y Xiong, L Sun, L Wang, K Wang… - Acta biomaterialia, 2019 - Elsevier
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a life-threatening
condition of critically-ill patients, characterized by overwhelming inflammatory responses in …