Atherosclerosis is the primary cause of heart disease and stroke and is thus the underlying
pathology of the leading causes of death in the western world. Although risk can be reduced …

Over the past two decades, the viewpoint of atherosclerosis has been replaced gradually by
a lipiddriven, chronic, low-grade inflammatory disease of the arterial wall. Current treatment …

Atherosclerotic coronary artery disease (CAD) results from build-up of cholesterol-rich
plaques in the walls of the coronary arteries and is a leading cause of death. Inflammation is …

The view of atherosclerosis as an inflammatory disease has emerged from observations of
immune activation and inflammatory signalling in human atherosclerotic lesions, from the …

Atherosclerosis, a dominant and growing cause of death and disability worldwide, involves
inflammation from its inception to the emergence of complications. Targeting inflammatory …

Abstract Rudolph Virchow (1821–1902) recognized inflammation in histological
preparations of coronary arteries and proposed that inflammation plays a causal role in …

Atherosclerosis constitutes the underlying disease to the clinical manifestations of
myocardial infarction, stroke, and gangrene. Despite the success of statins, prevention of …

Atherosclerosis represents the most common pathological substrate of coronary heart
disease (CHD), and the characterization of the disease as a chronic low-grade inflammatory …

Atherosclerotic coronary artery disease has a complex pathogenesis which extends beyond
cholesterol intimal infiltration. It involves chronic inflammation of the coronary artery wall …

Chronic inflammation is a central pathogenic mechanism of atherosclerosis induction and
progression. Vascular inflammation is associated with accelerated onset of late …