Patients' attitudes to discontinuing not-indicated long-term antidepressant use: barriers and facilitators

R Eveleigh, A Speckens, C van Weel… - Therapeutic …, 2019 - journals.sagepub.com
Background: Long-term antidepressant use has increased exponentially, though this is not
always according to guidelines. Our previous randomized controlled trial (RCT) showed that …

[HTML][HTML] Withdrawal of unnecessary antidepressant medication: a randomised controlled trial in primary care

R Eveleigh, E Muskens, P Lucassen, P Verhaak… - BJGP open, 2018 - bjgpopen.org
Background Antidepressant use has increased exponentially in recent decades, mostly due
to long continuation. Aim To assess the effectiveness of a tailored recommendation to …

Should I, can I, dare I? Patients' view on stopping long-term antidepressant use, a qualitative study

E Van Leeuwen, S Anthierens, ML van Driel… - Acta Clinica …, 2022 - Taylor & Francis
Background and aim The rise in long-term antidepressant use is concerning. Long-term
antidepressant (AD) use, much longer than recommended by guidelines, can result in risk of …

Compliance with antidepressants in a primary care setting, 1: beyond lack of efficacy and adverse events

K Demyttenaere, P Enzlin, W Dewé… - Journal of clinical …, 2001 - psychiatrist.com
Background: Treatment guidelines recommend antidepressant treatment be continued for at
least 6 months to ensure maximal improvement and to prevent relapse. Naturalistic studies …

Self-reported reasons for reducing or stopping antidepressant medications in primary care: thematic analysis of the diamond longitudinal study

A Coe, J Gunn, S Fletcher, E Murray… - Primary Health Care …, 2023 - cambridge.org
Background: Current treatment guidelines advise that the deprescribing of antidepressants
should occur around 6 months post-remission of symptoms. However, this is not routinely …

New users of antidepressant medications: first episode duration and predictors of discontinuation

CY Lu, E Roughead - European journal of clinical pharmacology, 2012 - Springer
Purpose Clinical guidelines recommend that antidepressant treatment should be continued
for at least 6 months. We examined persistence in patients initiated on an antidepressant …

Restarting antidepressant treatment following early discontinuation—a primary care database study

C Burton, AJ Cochran, IM Cameron - Family practice, 2015 - academic.oup.com
Background. Many patients in primary care stop antidepressant treatment after only one
prescription, so do not benefit from treatment. Some patients who stop initial antidepressant …

Why do patients discontinue antidepressant therapy early? A qualitative study

M Jaffray, AH Cardy, IC Reid… - The European journal of …, 2014 - Taylor & Francis
Background: Current guidelines for antidepressant prescribing are that treatment should be
continued following the resolution of symptoms: six months after a first episode and for at …

Barriers to discontinuing antidepressants in patients with depressive and anxiety disorders: a review of the literature and clinical recommendations

W Scholten, N Batelaan… - Therapeutic advances in …, 2020 - journals.sagepub.com
Use of antidepressants has recently increased, mainly caused by the increase of long-term
users. Although evidence-based indications for long-term use are lacking, it is assumed that …

'Never change a winning team': GPs' perspectives on discontinuation of long-term antidepressants

S Anthierens, ML van Driel, AD Sutter… - … Journal of Primary …, 2021 - Taylor & Francis
Background Long-term antidepressant use, much longer than recommended by guidelines,
can harm patients and generate unnecessary costs. Most antidepressants are prescribed by …