Background Increasingly, generic preference-based measures of health-related quality of
life (HRQOL) are used to estimate quality-adjusted life-years to inform resource allocation …

Objective In economic evaluation, health outcomes are commonly quantified using quality-
adjusted life-years (QALYs) derived from the preferences of a sample of the general …

Background Condition-specific measures are frequently used to assess the health-related
quality of life of people with multiple sclerosis (MS). Such measures are unsuitable for use in …

Background: Preference-based measures of health-related quality of life (HRQL) are used
as primary or secondary endpoints in multiple sclerosis (MS) research. Objective: The …

Background New interventions for multiple sclerosis (MS) commonly require a
demonstration of cost-effectiveness using health-related quality of life (HRQoL) utility values …

Background: Increasing use of the Quality-Adjusted Life-Year to inform resource allocation
decision-making has highlighted the importance of relating clinical and health-related …

abstract Objectives To estimate health state utility values (HSUVs) for multiple sclerosis (MS)
by key demographic and clinical characteristics. Methods Data from a UK prospective …

Background: Walking impairment has a major influence on the quality of life of people with
multiple sclerosis (MS). The Multiple Sclerosis Walking Scale (MSWS-12) assesses the …

Background A major debate in the quality-adjusted life-year (QALY) literature concerns
whose preferences should be used to estimate health state values (HSVs) and to calculate …

Health-related quality of life instruments are expected to be of particular value in routine care
of people with multiple sclerosis (MS), where they may facilitate the detection of disease …