Murine β-defensin-3 is an inducible peptide with limited tissue expression and broad-spectrum antimicrobial activity
RS Burd, JL Furrer, J Sullivan, AL Smith - Shock, 2002 - journals.lww.com
Abstract β-Defensins are cationic peptides produced by epithelial cells that have been
proposed to be an important component of immune function at mucosal surfaces. Similarities …
proposed to be an important component of immune function at mucosal surfaces. Similarities …
Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human β-defensin 3
Z Wu, DM Hoover, D Yang… - Proceedings of the …, 2003 - National Acad Sciences
Human defensins form a family of small, cationic, and Cys-rich antimicrobial proteins that
play important roles in innate immunity against invading microbes. They also function as …
play important roles in innate immunity against invading microbes. They also function as …
[HTML][HTML] Studies of the biological properties of human β-defensin 1
Defensins are small (30–45 amino acid residues) cationic proteins with broad antimicrobial
activity against many bacteria and fungi, some enveloped viruses, and other activities such …
activity against many bacteria and fungi, some enveloped viruses, and other activities such …
[HTML][HTML] Human defensins
JJ Schneider, A Unholzer, M Schaller… - Journal of molecular …, 2005 - Springer
Antimicrobial peptides are small, cationic, amphiphilic peptides of 12–50 amino acids with
microbicidal activity against both bacteria and fungi. The eukaryotic antimicrobial peptides …
microbicidal activity against both bacteria and fungi. The eukaryotic antimicrobial peptides …
Antimicrobial activity of human α‐defensin 6 analogs: insights into the physico‐chemical reasons behind weak bactericidal activity of HD6 in vitro
Human α‐defensin 6 (HD6), unlike other mammalian defensins, does not exhibit bactericidal
activity, particularly against aerobic bacteria. Monomeric HD6 has a tertiary structure similar …
activity, particularly against aerobic bacteria. Monomeric HD6 has a tertiary structure similar …
Antibacterial activities and conformations of bovine β-defensin BNBD-12 and analogs: structural and disulfide bridge requirements for activity
M Mandal, MV Jagannadham, R Nagaraj - Peptides, 2002 - Elsevier
Structure and biological activities of synthetic peptides corresponding to bovine neutrophil β-
defensin BNBD-12, GPLSC1GRNGGVC2IPIRC3 PVPMRQIGTC4 FGRPVKC5 C6RSW with …
defensin BNBD-12, GPLSC1GRNGGVC2IPIRC3 PVPMRQIGTC4 FGRPVKC5 C6RSW with …
Membrane disruptive antimicrobial activities of human β-defensin-3 analogs
US Sudheendra, V Dhople, A Datta, RK Kar… - European journal of …, 2015 - Elsevier
Human beta defensin-3 (HβD-3) is a host-defense protein exhibiting antibacterial activity
towards both Gram-negative and Gram-positive bacteria. There is considerable interest in …
towards both Gram-negative and Gram-positive bacteria. There is considerable interest in …
High‐Level Expression of a Soluble Functional Antimicrobial Peptide, Human β‐Defensin 2, in Escherichia coli
Z Xu, L Peng, Z Zhong, X Fang… - Biotechnology progress, 2006 - Wiley Online Library
In this work, taking human β‐defensin‐2 (HBD2) as a demonstrative molecule, the strategies
for high efficient production of functional human β‐defensins in E. coli were studied. Fusion …
for high efficient production of functional human β‐defensins in E. coli were studied. Fusion …
Structure determination of human and murine β‐defensins reveals structural conservation in the absence of significant sequence similarity
F Bauer, K Schweimer, E Klüver… - Protein …, 2001 - Wiley Online Library
Defensins are cationic and cysteine‐rich peptides that play a crucial role in the host defense
against microorganisms of many organisms by their capability to permeabilize bacterial …
against microorganisms of many organisms by their capability to permeabilize bacterial …