Carbapenems are potent β-lactams with activity against extended-spectrum
cephalosporinases and β-lactamases. These antibiotics, derived from thienamycn, a …

Carbapenem resistance among Enterobacteriaceae is a major concern that is increasingly
reported worldwide. The objective of this study is to determine the incidence of carbapenem …

Plasmid-acquired carbapenemases in Enterobacteriaceae, which were first discovered in
Europe in the 1990s, are now increasingly being identified at an alarming rate. Although …

Carbapenemases are β-lactamases belonging to different Ambler classes (A, B, D) and can
be encoded by both chromosomal and plasmid-mediated genes. These enzymes represent …

Materials and Methods A total of 260 isolates of carbapenem resistant E. coli (n= 57),
Klebsiella spp.(n= 85), Pseudomonas aeruginosa (n= 60), and Acinetobacter baumannii …

Carbapenem resistance is a major and an on-going public health problem globally. It occurs
mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas …

Background Carbapenem resistance is endemic in the Indian sub-continent. In this study,
carbapenem resistance rates and the prevalence of different carbapenemases were …

Emergence and spread of carbapenemase-producing Enterobacteriaceae (CPE) are two of
the major problems currently threatening global public health. In Nigeria, interest in CPE is …

Singapore is an international travel and medical hub and faces a genuine threat for import
and dissemination of bacteria with broad-spectrum resistance. In this review, we described …

Carbapenemases involved in acquired carbapenem resistance in Enterobacteriaceae
belong to Ambler class A serin β-lactamases, class B metallo-β-lactamases (MBL) or class D …