There has been growing evidence that heat-shock protein (HSP) functions as an
endogenous immunomodulator for innate and adaptive immune responses. Since HSPs …

Heat shock proteins (Hsp) inhabit intracellular locales where at least one of their functions,
molecular chaperoning of other proteins, has been firmly established. However, there are …

Cells react to physical (eg, heat) or chemical (eg, anoxia, low pH) stressors, mounting a
stress (heat-shock) response. Most genes are turned down or off, while a few are activated …

This book will deal with heat shock proteins and more generally with stress-related inducible
gene expression as a pleiotropic adaptive response to stress. It presents a textbook-like …

Stress or heat shock proteins (HSPs) are remarkably conserved in all living organisms. Their
expression is induced in response to a variety of physiological and environmental insults. In …

As molecular chaperones, heat-shock proteins (HSPs) function to limit protein aggregation,
facilitate protein refolding and chaperone other proteins. Under conditions of cellular stress …

We recently elucidated a novel function for the 70-kDa heat shock protein (HSP70) as a
chaperone and a cytokine, a chaperokine in human monocytes. Here we show that peptide …

Since its discovery in 1962 by Ritossa, the heat shock response has been extensively
studied by a number of investigators to understand the molecular mechanism underlying the …

Cells have developed complex ways to respond to various stresses. Interestingly, stresses
such as heat, ischaemia and radiation can induce different cellular responses depending on …

Evidence is mounting to support the theory thatdanger'associated with tissue damage and
stress is a level of control of antigen-specific immune responses. Heat shock proteins are …