[HTML][HTML] In vitro evaluation, in silico studies and toxicological assay of some xanthones as potential Leishmania donovani inhibitors
Xanthones are naturally occurring compounds that exist in some higher plants, fungi and
lichen. Natural and synthetic xanthones have shown diverse biological and pharmacological …
lichen. Natural and synthetic xanthones have shown diverse biological and pharmacological …
[PDF][PDF] In Silico Research of New Therapeutics Rotenoids Derivatives against Leishmania amazonensis Infection. Biology 2022, 11, 133
A Vicente-Barrueco, ÁC Román, T Ruiz-Téllez… - 2022 - academia.edu
Yearly, 1,500,000 cases of leishmaniasis are diagnosed, causing thousands of deaths. To
advance in its therapy, we present an interdisciplinary protocol that unifies ethnobotanical …
advance in its therapy, we present an interdisciplinary protocol that unifies ethnobotanical …
Insights into the molecular basis of some chalcone analogues as potential inhibitors of Leishmania donovani: An integrated in silico and in vitro study
Protozoal infections caused by species belonging to Leishmania donovani complex are
responsible for the most severe form of leishmaniasis, especially in Sudan and other …
responsible for the most severe form of leishmaniasis, especially in Sudan and other …
[HTML][HTML] Synthesis and biological evaluation of 9-aryl-1, 8-dioxo-octahydroxanthene derivatives as antileishmanial agents
K Lodha, D Wavhal, N Bhujbal, P Mazire, S Bhujbal… - Results in …, 2023 - Elsevier
In the current research, we designed and synthesized various derivatives of 9-aryl-1, 8-dioxo-
octahydroxanthene using flow chemistry technique and explored in vitro study for …
octahydroxanthene using flow chemistry technique and explored in vitro study for …
In Silico Research of New Therapeutics Rotenoids Derivatives against Leishmania amazonensis Infection
A Vicente-Barrueco, ÁC Román, T Ruiz-Téllez… - Biology, 2022 - mdpi.com
Simple Summary In this work, we show bioinformatic procedures to search for new drugs
form plant-derived molecules, previously described in ethnobotany as useful for the …
form plant-derived molecules, previously described in ethnobotany as useful for the …
Molecular modeling studies of benzimidazolyl-chalcones as antileishmanial agents using qsar, docking, ADME and molecular dynamics studies
DUJP N'guessan, AA Alzain, EM Adouko… - Journal of Applied …, 2021 - japsr.in
Introduction: Present leishmaniasis treatment regimen has many limitations including severe
adverse effects, toxicity, and Leishmania strains resistance. In the present study, the …
adverse effects, toxicity, and Leishmania strains resistance. In the present study, the …
Coumarin analogues as a potential inhibitor of leishmaniasis: A multi-targeting protein inhibition approach by molecular docking
K Kapoor - Universal Journal of Pharmaceutical Research, 2019 - ujpronline.com
Objective: Leishmaniasis is one of the most dreadful diseases as a leading cause of death in
most of the developed countries. Objective of the current work was to identify more potent …
most of the developed countries. Objective of the current work was to identify more potent …
Identification of 3-Methoxycarpachromene and Masticadienonic Acid as New Target Inhibitors against Trypanothione Reductase from Leishmania Infantum Using …
Polyphenolic and Terpenoids are potent natural antiparasitic compounds. This study aimed
to identify new drug against Leishmania parasites, leishmaniasis's causal agent. A new in …
to identify new drug against Leishmania parasites, leishmaniasis's causal agent. A new in …
Computational studies on new Leishmanial drug targets against Quercetin
K Jyothi, V Sivaranjani, U Pavithra… - Indian Journal of …, 2022 - op.niscpr.res.in
Leishmaniasis, a parasitic disease caused by Leishmania parasite which resides in the
infected sand flies. Control of Leishmaniasis remains a source of grave concern worldwide …
infected sand flies. Control of Leishmaniasis remains a source of grave concern worldwide …
2,3-Dihydroquinazolin-4(1H)-one as a New Class of Anti-Leishmanial Agents: A Combined Experimental and Computational Study
Leishmaniasis is a neglected parasitic disease caused by various Leishmania species. The
discovery of new protozoa drugs makes it easier to treat the disease; but, conventional …
discovery of new protozoa drugs makes it easier to treat the disease; but, conventional …