Stroke is a lethal cerebral disease with severe sequelae and high mortality. Microglia, the
main immune cell in the cerebrum, possess therapeutic potential for strokes as its specific …

Stroke is a threatening cerebrovascular disease caused by thrombus with high morbidity
and mortality rates. Neutrophils are the first to be recruited in the brain after stroke, which …

The incidence of ischemic stroke (IS) is rising in tandem with the global aging population.
There is an urgent need to delve deeper into the pathological mechanisms and develop new …

Stroke is a primary cause of death and disability worldwide, while effective and safe drugs
remain to be developed for its clinical treatment. Herein, we report bioactive nanoparticle …

Neurological diseases are of widespread concern due to high disability and mortality.
Nanodrugs have been developed for the treatment of a wide range of neurological …

Delivery of macromolecular drugs to the brain is impeded by the blood brain barrier. The
recruitment of leukocytes to lesions in the brain, a typical feature of neuroinflammation …

Rational design of nanomedicine to accelerate thrombolysis and sequentially avoid
thrombolysis-mediated reperfusion injury is still a challenge. Here, we develop a biomimetic …

Ischemic stroke is one of the main issues threatening human health worldwide, and it is also
the main cause of permanent disability in adults. Energy consumption and hypoxia after …

Stroke is one of the most prevalent diseases worldwide caused primarily by a thrombotic
vascular occlusion that leads to cell death. To date, t-PA (tissue-type plasminogen activator) …

Human neutrophils are the most abundant circulating leukocytes and contribute to acute and
chronic inflammatory disorders. Neutrophil apoptosis is programed cell death to maintain …