There is a rich history of neural progenitor transplantation for repair of the injured central
nervous system (Anderson, Howland, & Reier, 1995; Bonner & Steward, 2015; Jakeman & …

Cellular transplantation for repair of the injured spinal cord has a rich history with strategies
focused on neuroprotection, immunomodulation, and neural reconstruction. The goal of the …

✓ Despite advances in medical and surgical care, the current clinical therapies for spinal
cord injury (SCI) are largely ineffective. During the last 2 decades, the search for new …

As our understanding and ability to direct the differentiation of stem cells grows, specific
targets and strategies to incorporate them are essential to define. Any cell-based …

Traumatic spinal cord injury (SCI) results in devastating and often permanent disability for
which no effective biologic therapies exist. The injury initiates a cascade of complex …

Affecting young people during the most productive period of their lives, spinal cord injury
(SCI) is a devastating problem for modern society. In the past, treating SCI seemed …

Spinal cord injury typically results in permanent disability. Many studies have indicated that
transplantation of several different types of stem cells promotes functional recovery in animal …

Spinal cord injuries (SCIs) are life-changing events that often irrevocably alter the lives of
injured individuals and their family members. There are more than 300,000 people living …

Spinal cord injury (SCI) invariably results in the loss of neurons and axonal degeneration at
the lesion site, leading to permanent paralysis and loss of sensation. There has been no …

The complex pathology of spinal cord injury (SCI), involving a cascade of secondary events
and the formation of inhibitory barriers, hampers regeneration across the lesion site and …