Metabolism and polarization regulation of macrophages in the tumor microenvironment

J Wang, S Mi, M Ding, X Li, S Yuan - Cancer letters, 2022 - Elsevier
The occurrence and development of tumors depend on the tumor microenvironment (TME),
which consists of various types of cellular and acellular components. Tumor-associated …

Diverse macrophages polarization in tumor microenvironment

I Rhee - Archives of pharmacal research, 2016 - Springer
Macrophages are traditional innate immune cells that play critical roles in the clearance of
pathogens and the maintenance of tissue homeostasis. Accumulating evidence proves that …

[HTML][HTML] Metabolism, metabolites, and macrophages in cancer

M Li, Y Yang, L Xiong, P Jiang, J Wang, C Li - Journal of hematology & …, 2023 - Springer
Tumour-associated macrophages (TAMs) are crucial components of the tumour
microenvironment and play a significant role in tumour development and drug resistance by …

Metabolic regulation of macrophage polarization in cancer

K Mehla, PK Singh - Trends in cancer, 2019 - cell.com
Macrophages act as scavengers, modulating the immune response against pathogens and
maintaining tissue homeostasis. Metabolism governs macrophage differentiation …

[HTML][HTML] Metabolic cancer-macrophage crosstalk in the tumor microenvironment

KE Goede, AJM Driessen, J Van den Bossche - Biology, 2020 - mdpi.com
Simple Summary Tumors often include many immune cells that are theoretically able to
combat tumor growth. Yet, tumors can induce immune functions that support tumor growth …

[HTML][HTML] Transcriptional, epigenetic and metabolic programming of tumor-associated macrophages

I Larionova, E Kazakova, M Patysheva… - Cancers, 2020 - mdpi.com
Macrophages are key innate immune cells in the tumor microenvironment (TME) that
regulate primary tumor growth, vascularization, metastatic spread and tumor response to …

[HTML][HTML] The role of metabolic plasticity of tumor-associated macrophages in shaping the tumor microenvironment immunity

MN Hasan, O Capuk, SM Patel, D Sun - Cancers, 2022 - mdpi.com
Simple Summary Tumor associated macrophages (TAMs) support disease progression by
providing tumor cells cytokines and chemokines necessary for malignant growth and …

Tumor associated macrophages and neutrophils in tumor progression

MR Galdiero, C Garlanda, S Jaillon… - Journal of cellular …, 2013 - Wiley Online Library
Tumor‐associated macrophages (TAMs) are a key component of the tumor
microenvironment and orchestrate various aspects of cancer. Diversity and plasticity are …

Immunometabolic attributes and mitochondria-associated signaling of Tumor-Associated Macrophages in tumor microenvironment modulate cancer progression

S Dubey, S Ghosh, D Goswami, D Ghatak… - Biochemical …, 2023 - Elsevier
Macrophages are specialized immune cells, which have the capacity to phagocytize and
destroy the target cells, including tumor cells. Some macrophages, however on their way to …

[HTML][HTML] Metabolic reprogramming induces macrophage polarization in the tumor microenvironment

S Wang, G Liu, Y Li, Y Pan - Frontiers in immunology, 2022 - frontiersin.org
Macrophages are one of the most important cells in the innate immune system, they are
converted into two distinct subtypes with completely different molecular phenotypes and …