Modeling the growth dynamics of glioblastoma using magnetic resonance imaging

C Badve, AE Sloan - Neuro-oncology, 2015 - academic.oup.com
The significant intra-and intertumoral heterogeneity of gliomas, an improved appreciation for
the biological differences among individual tumors, and the complexity of response …

Growth dynamics of untreated glioblastomas in vivo

AL Stensjøen, O Solheim, KA Kvistad… - Neuro …, 2015 - academic.oup.com
Background Glioblastomas are primary malignant brain tumors with a dismal prognosis.
Knowledge of growth rates and underlying growth dynamics is useful for understanding …

Modeling of glioma growth with mass effect by longitudinal magnetic resonance imaging

B Tunç, DA Hormuth II, G Biros… - IEEE Transactions on …, 2021 - ieeexplore.ieee.org
It is well-known that expanding glioblastomas typically induce significant deformations of the
surrounding parenchyma (ie, the so-called “mass effect”). In this study, we evaluate the …

Mathematical modeling of glioma on MRI

E Mandonnet - Revue neurologique, 2011 - Elsevier
The advent of Magnetic Resonance Imaging (MRI) has enabled quantification of glioma
growth with millimetric accuracy. Thus, it is now possible to monitor the growth curve of …

Mathematical modeling of low-grade glioma

E Mandonnet - Bulletin de L'academie Nationale de Medecine, 2011 - europepmc.org
Magnetic resonance imaging can be used to quantify low-grade glioma growth with
millimetric accuracy. Mathematical modeling helps to analyze individual glioma growth …

Prognostic significance of growth kinetics in newly diagnosed glioblastomas revealed by combining serial imaging with a novel biomathematical model

CH Wang, JK Rockhill, M Mrugala, DL Peacock, A Lai… - Cancer research, 2009 - AACR
Glioblastomas are the most aggressive primary brain tumors, characterized by their rapid
proliferation and diffuse infiltration of the brain tissue. Survival patterns in patients with …

Histopathologic features in relation to pretreatment tumor growth in patients with glioblastoma

VE Mikkelsen, AL Stensjøen, EM Berntsen… - World Neurosurgery, 2018 - Elsevier
Background Rapid growth is a well-known property of glioblastoma (GBM); however, growth
rates vary among patients. Mechanisms behind such variation have not been widely studied …

Does pretreatment tumor growth hold prognostic information for patients with glioblastoma?

AL Stensjøen, EM Berntsen, VE Mikkelsen, SH Torp… - World Neurosurgery, 2017 - Elsevier
Background Glioblastomas are highly aggressive and heterogeneous tumors, both in terms
of patient outcome and molecular profile. Magnetic resonance imaging of tumor growth …

Contrast‐enhancing tumor growth dynamics of preoperative, treatment‐naive human glioblastoma

BM Ellingson, HN Nguyen, A Lai, RE Nechifor, O Zaw… - Cancer, 2016 - Wiley Online Library
BACKGROUND Little is known about the natural growth characteristics of untreated
glioblastoma before surgical or therapeutic intervention, because patients are rapidly treated …

[PDF][PDF] Spatially quantifying microscopic tumor invasion and proliferation using a voxel-wise analytical solution to a glioma growth model and serial diffusion MRI

BM Ellingson, SD Rand, MG Malkin, R Prost… - Proc Intl Soc Mag …, 2010 - academia.edu
Glioblastoma multiforme (GBM) is a particular type of infiltrative malignant brain tumor
trademarked by a very poor patient prognosis. Despite advancements in surgical …