Early add-on lacosamide in a real-life setting: results of the REALLY study
V Villanueva, M Garcés, E López-Gomáriz… - Clinical drug …, 2015 - Springer
Background and objectives Many patients with epilepsy are treated with antiepileptic drug
(AED) polytherapy. Several factors influence the choice of early add-on therapy, and …
(AED) polytherapy. Several factors influence the choice of early add-on therapy, and …
[HTML][HTML] Lacosamide monotherapy for partial onset seizures
S Lattanzi, C Cagnetti, N Foschi, L Provinciali… - Seizure, 2015 - Elsevier
Purpose To evaluate the 1-year efficacy and safety of oral lacosamide as conversion
monotherapy in adult patients with partial onset seizures with or without generalization …
monotherapy in adult patients with partial onset seizures with or without generalization …
LACONORTE study: efficacy and security of lacosamide as first add-on therapy for focal-onset epilepsy in real-life setting
A Muñoz-Lopetegi, FJ López-González… - Epilepsy Research, 2018 - Elsevier
Rationale Many patients with epilepsy need a second antiepileptic drug (AED), due either to
inefficacy or side effects of the first tried one. We evaluated the efficacy and safety of …
inefficacy or side effects of the first tried one. We evaluated the efficacy and safety of …
Control of seizures in different stages of partial epilepsy: LACO-EXP, a Spanish retrospective study of lacosamide
V Villanueva, FJ López, JM Serratosa… - Epilepsy & Behavior, 2013 - Elsevier
Lacosamide is approved as adjunctive therapy for focal epilepsies. The number of
antiepileptic drugs (AEDs) tried is associated with prognosis. This multicenter, retrospective …
antiepileptic drugs (AEDs) tried is associated with prognosis. This multicenter, retrospective …
Long‐term adjunctive lacosamide treatment in patients with partial‐onset seizures
F Rosenow, A Kelemen… - Acta Neurologica …, 2016 - Wiley Online Library
Objective To evaluate long‐term (up to 5.5 years) safety, seizure reduction, and
maintenance of efficacy of the antiepileptic drug (AED) lacosamide as adjunctive treatment …
maintenance of efficacy of the antiepileptic drug (AED) lacosamide as adjunctive treatment …
Safety and efficacy of adjunctive lacosamide among patients with partial-onset seizures in a long-term open-label extension trial of up to 8 years
W Rosenfeld, NB Fountain, G Kaubrys… - Epilepsy & Behavior, 2014 - Elsevier
Long-term (up to 8 years of exposure) safety and efficacy of the antiepileptic drug
lacosamide was evaluated in this open-label extension trial (SP615 [ClinicalTrials. gov …
lacosamide was evaluated in this open-label extension trial (SP615 [ClinicalTrials. gov …
Long‐term safety and efficacy in patients with uncontrolled partial‐onset seizures treated with adjunctive lacosamide: results from a Phase III open‐label extension …
A Husain, S Chung, E Faught, J Isojarvi, C McShea… - …, 2012 - Wiley Online Library
Purpose: To evaluate the long‐term (up to 5 years exposure) safety and efficacy of
lacosamide as adjunctive therapy in patients with uncontrolled partial‐onset seizures taking …
lacosamide as adjunctive therapy in patients with uncontrolled partial‐onset seizures taking …
[HTML][HTML] Efficacy and safety of lacosamide as first add-on or later adjunctive treatment for uncontrolled partial-onset seizures: a multicentre open-label trial
WW Zadeh, A Escartin, W Byrnes, F Tennigkeit… - Seizure, 2015 - Elsevier
Purpose To evaluate the efficacy and safety of lacosamide administered as either first add-
on or later add-on antiepileptic drug (AED) therapy for patients with uncontrolled partial …
on or later add-on antiepileptic drug (AED) therapy for patients with uncontrolled partial …
A noninterventional study evaluating the effectiveness and safety of lacosamide added to monotherapy in patients with epilepsy with partial‐onset seizures in daily …
U Runge, S Arnold, C Brandt, F Reinhardt, F Kühn… - …, 2015 - Wiley Online Library
Objective Evidence for the efficacy and safety of adjunctive lacosamide in the treatment of
partial‐onset seizures (POS) was gained during placebo‐controlled clinical trials in patients …
partial‐onset seizures (POS) was gained during placebo‐controlled clinical trials in patients …
Safety and tolerability of adjunctive lacosamide intravenous loading dose in lacosamide‐naive patients with partial‐onset seizures
NB Fountain, G Krauss, J Isojarvi, D Dilley, P Doty… - …, 2013 - Wiley Online Library
Purpose: To examine the safety and tolerability of rapidly initiating adjunctive lacosamide via
a single intravenous loading dose followed by twice‐daily oral lacosamide in lacosamide …
a single intravenous loading dose followed by twice‐daily oral lacosamide in lacosamide …