Objective—Recent evidence suggests that dendritic cells may play an important role in
atherosclerosis. Based primarily on previous in vitro studies, we hypothesized that …

The contribution of intimal cell proliferation to the formation of early atherosclerotic lesions is
poorly understood. We combined 5-bromo-2′-deoxyuridine pulse labeling with sensitive en …

Granulocyte-macrophage colony-stimulating factor (GM-CSF), one of a family of cytokines
that regulate proliferation in macrophages and other types of cells, has been implicated in …

Recent studies have documented that macrophages are a significant cell component of
atherosclerotic lesions and may play a significant role in the pathogenesis of these lesions. It …

Rationale: Atherosclerosis is an inflammatory disease in which leukocytes and oxidatively
modified lipids accumulate in the arterial intima. Previously, we showed that dendritic cells …

Background—A cytokine network is involved in atherogenesis. This study was conducted to
investigate the effects of granulocyte-macrophage colony–stimulating factor (GM-CSF) on …

Atherosclerosis is a complex chronic disease. The accumulation of myeloid cells in the
arterial intima, including macrophages and dendritic cells (DCs), is a feature of early stages …

Dendritic cells constitute a unique family of cells able to induce primary immune responses.
Over the past decade, immunologists have been increasingly preoccupied with dendritic …

OBJECTIVES: We characterized the transcriptional profiles of GM-CSF-(GM-MØ) and M-CSF-
induced macrophages (M-MØ) and investigated in situ a subset of differentially expressed …

A complex role has been described for dendritic cells (DCs) in the potentiation and control of
vascular inflammation and atherosclerosis. Resident vascular DCs are found in the intima of …