We evaluated the lineage specificity of CD79a in acute leukemias using 3-color flow
cytometry in 58 consecutive cases. A panel of cell-surface antigens, including myeloid …

In the t (15; 17) translocation of acute promyelocytic leukemia (APL) at least three regions of
the PML gene are involved in the reciprocal translocation between the PML and the RAR …

We report on a single‐center experience about the characteristics and outcome of 36 acute
promyelocytic leukemia (APL) patients observed at our Department of Hematology between …

Background Prompt diagnosis of acute promyelocytic leukemia (APL) is critical for patient
care. In this study, we aimed to characterize the immunophenotype of APL and explore …

Abstract The chromosomal translocation t (15; 17)(q22: 21) of acute promyelocytic leukemia
(APL) fuses PML, a novel gene, with RAR alpha, a retinoic acid receptor gene. PML-RAR …

Acute promyelocytic leukemia (APL) accounts for approximately 10% of cases of acute
myeloid leukemia (AML). Distinctive features of this disorder at the time of diagnosis include …

Review Page 1 Review THE PATHOGENESIS OF ACUTE PROMYELOCYTIC LEUKAEMIA:
EVALUATION OF THE ROLE OF MOLECULAR DIAGNOSIS AND MONITORING IN THE …

A fundamental issue in cancer biology is the identification of the target cell in which the
causative molecular lesion arises. Acute myeloid leukemia (AML) is thought to reflect the …

We present our experience with immunophenotypic characteristics of benign and malignant
myeloid populations, with emphasis on differential diagnosis especially between …

Acute promyelocytic leukemia (APL) is a relatively common form of acute myeloid leukemia
(AML) that has an excellent prognosis. In contrast, secondary acute myeloid leukemias …