Patients with acute promyelocytic leukemia (APL) show other chromosome aberrations in
addition to t (15; 17) but their influence on the clinical outcome is still unclear. We have …

In spite of the recent improvement in the outcome of acute promyelocytic leukaemia (APL)
with treatment combining all trans retinoic acid (ATRA) and chemotherapy (CT), some …

Acute promyelocytic leukemia (APL) is a rare leukemia characterized by the balanced
reciprocal translocation between the promyelocytic leukemia gene on chromosome 15 and …

Acute promyelocytic leukaemia (APL) has been associated with a favourable prognosis in
many studies of acute myeloid leukaemia. A series of 54 patients treated at the Royal …

Therapy‐related acute promyelocytic leukemia (t‐APL) is a well‐recognized form of APL for
which the underlying etiology has been well characterized. The pathogenesis of de novo (dn …

Monoclonal B-cell lymphocytosis (MBL) is defined as an asymptomatic expansion of clonal
B cells with less than 5× 109/L cells in the peripheral blood and without other manifestations …

PURPOSE: To investigate the frequency of p15 and p16 gene promoter methylation in acute
promyelocytic leukemia (APL), and to define its value in the detection of minimal residual …

Acute promyelocytic leukaemia (APL), characterized by a specific PML‐RARα fusion gene
resulting from translocation t (15; 17) and by a high response rate to differentiation therapy …

In a cohort of 67 adult patients with newly diagnosed untreated acute promyelocytic
leukemia (APL), the initial clinical and biological parameters were submitted to multivariate …

In all, 17 consecutive patients in hematological complete remission (HCR) of acute
promyelocytic leukemia (APL) received allogeneic stem cell transplantation (SCT) from an …