[HTML][HTML] Statistical analysis for genome-wide association study
In the past few years, genome-wide association study (GWAS) has made great successes in
identifying genetic susceptibility loci underlying many complex diseases and traits. The …
identifying genetic susceptibility loci underlying many complex diseases and traits. The …
A road map for efficient and reliable human genome epidemiology
Networks of investigators have begun sharing best practices, tools and methods for analysis
of associations between genetic variation and common diseases. A Network of Investigator …
of associations between genetic variation and common diseases. A Network of Investigator …
Beyond odds ratios—communicating disease risk based on genetic profiles
The brisk discovery of novel inherited disease markers by genome-wide association (GWA)
studies has raised expectations for predicting disease risk by analysing multiple common …
studies has raised expectations for predicting disease risk by analysing multiple common …
Next generation analytic tools for large scale genetic epidemiology studies of complex diseases
LE Mechanic, HS Chen, CI Amos… - Genetic …, 2012 - Wiley Online Library
Over the past several years, genome‐wide association studies (GWAS) have succeeded in
identifying hundreds of genetic markers associated with common diseases. However, most …
identifying hundreds of genetic markers associated with common diseases. However, most …
Bringing genome-wide association findings into clinical use
TA Manolio - Nature Reviews Genetics, 2013 - nature.com
Genome-wide association studies (GWASs) have been heralded as a major advance in
biomedical discovery, having identified~ 2,000 robust associations with complex diseases …
biomedical discovery, having identified~ 2,000 robust associations with complex diseases …
Genomewide association studies and human disease
J Hardy, A Singleton - New England Journal of Medicine, 2009 - Mass Medical Soc
Genomewide Association Studies and Human Disease | New England Journal of Medicine Skip
to main content The New England Journal of Medicine homepage Advanced Search SEARCH …
to main content The New England Journal of Medicine homepage Advanced Search SEARCH …
Association study designs for complex diseases
Assessing the association between DNA variants and disease has been used widely to
identify regions of the genome and candidate genes that contribute to disease. However …
identify regions of the genome and candidate genes that contribute to disease. However …
GWASdb: a database for human genetic variants identified by genome-wide association studies
Recent advances in genome-wide association studies (GWAS) have enabled us to identify
thousands of genetic variants (GVs) that are associated with human diseases. As next …
thousands of genetic variants (GVs) that are associated with human diseases. As next …
[PDF][PDF] A short history of the genome-wide association study: where we were and where we are going
S Ikegawa - Genomics & informatics, 2012 - synapse.koreamed.org
Recent rapid advances in genetic research are ushering us into the genome sequence era,
where an individual's genome information is utilized for clinical practice. The most …
where an individual's genome information is utilized for clinical practice. The most …
15 years of GWAS discovery: realizing the promise
It has been 15 years since the advent of the genome-wide association study (GWAS) era.
Here, we review how this experimental design has realized its promise by facilitating an …
Here, we review how this experimental design has realized its promise by facilitating an …