Background The number of genome-wide association studies (GWAS) is growing rapidly
leading to the discovery and replication of many new disease loci. Combining results from …

Genome-wide association studies are revolutionizing the search for the genes underlying
human complex diseases. The main decisions to be made at the design stage of these …

Over the last few years, many new genetic associations have been identified by genome‐
wide association studies (GWAS). There are potentially many uses of these identified …

We have derived a versatile gene-based test for genome-wide association studies (GWAS).
Our approach, called VEGAS (versatile gene-based association study), is applicable to all …

Genetic factors strongly affect susceptibility to common diseases and also influence disease-
related quantitative traits. Identifying the relevant genes has been difficult, in part because …

We have followed with interest the discussion in your journal and elsewhere of the
contribution of genome-wide association studies (GWAS) to the elucidation of the aetiology …

Genome-wide association study (GWAS) technology has been a primary method for
identifying the genes responsible for diseases and other traits for the past 10 years. Over …

To facilitate broad and convenient integrative visualization of and access to GWAS data, we
have created the GWAS Central resource (http://www. gwascentral. org). This database …

Following the identification of several disease-associated polymorphisms by genome-wide
association (GWA) analysis, interest is now focusing on the detection of effects that, owing to …

Genetic effects for common variants affecting complex disease risk are subtle. Single
genome-wide association (GWA) studies are typically underpowered to detect these effects …