Synthesis, biological evaluation, and molecular docking of new benzimidazole-1, 2, 3-triazole hybrids as antibacterial and antitumor agents
S Ahmed Saleh Alzahrani, S Nazreen… - Polycyclic Aromatic …, 2023 - Taylor & Francis
A new series of benzimidazole-1, 2, 3-triazole hybrids have been successfully accomplished
by the Click chemistry of different aromatic azides and propargylated benzimidazole (4). The …
by the Click chemistry of different aromatic azides and propargylated benzimidazole (4). The …
Synthesis, antimicrobial activity and molecular docking of novel benzimidazole conjugated 1, 2, 3-triazole analogues
V Mallikanti, V Thumma, R Matta, KR Valluru… - Chemical Data …, 2023 - Elsevier
A library of novel benzimidazole based 1, 2, 3-triazoles were synthesized by a series of
reactions containing Suzuki coupling, cyclization and microwave assisted copper catalyzed …
reactions containing Suzuki coupling, cyclization and microwave assisted copper catalyzed …
Benzimidazole‐1, 3, 4‐Oxadiazole Hybrids: Synthesis, Anticancer Evaluation, Docking and DFT Studies
SAS Alzahrani, S Nazreen, AA Elhenawy… - …, 2022 - Wiley Online Library
In the present work, new benzimidazole based 1, 3, 4‐oxadiazole linked thioacetamide
conjugates have been synthesized and evaluated for antiproliferative activity. Formation of …
conjugates have been synthesized and evaluated for antiproliferative activity. Formation of …
[HTML][HTML] Rational design, synthesis, and anti-cancer evaluation of amide derivatives of 1, 3, 4-Thiadiazole benzimidazoles
VN Kumar, M Nookaraju, KS Jella, L Eppakayala - Results in Chemistry, 2024 - Elsevier
A series of amide derivatives of 1, 3, 4-thiadiazole-benzimidazole (13a-j) has been
designed, synthesized and screened for their anticancer activities against human breast …
designed, synthesized and screened for their anticancer activities against human breast …
Identification of new benzimidazole-triazole hybrids as anticancer agents: multi-target recognition, in vitro and in silico studies
Multi-target inhibitors represent useful anticancer agents with superior therapeutic attributes.
Here in, two novel series of benzimidazole-triazole hybrids were designed, synthesised as …
Here in, two novel series of benzimidazole-triazole hybrids were designed, synthesised as …
Synthesis, antiproliferative, docking and DFT studies of benzimidazole derivatives as EGFR inhibitors
HA Alzahrani, MM Alam, AA Elhenawy… - Journal of Molecular …, 2022 - Elsevier
In the present work, new benzimidazole linked 1, 2, 3-triazole hybrids have been
synthesized and screened for antiproliferative and EGFR kinase inhibitory activities. The …
synthesized and screened for antiproliferative and EGFR kinase inhibitory activities. The …
[HTML][HTML] Synthesis of some benzimidazole derivatives bearing 1, 3, 4-oxadiazole moiety as anticancer agents
B Mochona, E Mazzio, M Gangapurum… - Chemical science …, 2015 - ncbi.nlm.nih.gov
In an effort to establish new benzimidazole related structural leads with improved anticancer
activity, several new benzimidazole derivatives (5a–i) with 1, 3, 4-oxadiazole scaffold …
activity, several new benzimidazole derivatives (5a–i) with 1, 3, 4-oxadiazole scaffold …
Cell cycle arrest and apoptosis-inducing ability of benzimidazole derivatives: design, synthesis, docking, and biological evaluation
S Nazreen, ASA Almalki, SEI Elbehairi, AA Shati… - Molecules, 2022 - mdpi.com
In the current study, new benzimidazole-based 1, 3, 4-oxadiazole derivatives have been
synthesized and characterized by NMR, IR, MS, and elemental analysis. The final …
synthesized and characterized by NMR, IR, MS, and elemental analysis. The final …
Novel benzoxepine-1, 2, 3-triazole hybrids: synthesis and pharmacological evaluation as potential antibacterial and anticancer agents
N Kuntala, JR Telu, V Banothu, SB Nallapati… - …, 2015 - pubs.rsc.org
A number of pre-designed benzoxepine-1, 2, 3-triazole hybrids were synthesized for the first
time using a Cu-catalyzed azide–alkyne cycloaddition (CuAAC) strategy. Thus, a remarkably …
time using a Cu-catalyzed azide–alkyne cycloaddition (CuAAC) strategy. Thus, a remarkably …
Synthesis, Anticancer Activity and Molecular Docking Studies of Hybrid Benzimidazole-1,3,4-Oxadiazol-2-N-Alkyl/Aryl Amines
R Katikireddy, S Marri, R Kakkerla… - Polycyclic Aromatic …, 2022 - Taylor & Francis
In the present study, the synthesis of benzimdazolyl 2-amino-1, 3, 4-oxadiazole derivatives
(5a-j) and their in vitro anticancer activities against HeLa, MCF7, A549, and HEK293 cell …
(5a-j) and their in vitro anticancer activities against HeLa, MCF7, A549, and HEK293 cell …