Pathogenesis of Yersinia pestis Infection in BALB/c Mice: Effects on Host Macrophages and Neutrophils

RA Lukaszewski, DJ Kenny, R Taylor… - Infection and …, 2005 - Am Soc Microbiol
The pathogenesis of infection with Yersinia pestis, the causative agent of plague, was
examined following subcutaneous infection of BALB/c mice with a fully virulent strain …

Kinetics of innate immune response to Yersinia pestis after intradermal infection in a mouse model

CF Bosio, CO Jarrett, D Gardner… - Infection and …, 2012 - Am Soc Microbiol
ABSTRACT A hallmark of Yersinia pestis infection is a delayed inflammatory response early
in infection. In this study, we use an intradermal model of infection to study early innate …

Delayed inflammatory response to primary pneumonic plague occurs in both outbred and inbred mice

SS Bubeck, AM Cantwell, PH Dube - Infection and immunity, 2007 - Am Soc Microbiol
Yersinia pestis is the causative agent of plague, a disease that can manifest as either
bubonic or pneumonic plague. An interesting feature of plague is that it is a rapidly …

Yersinia pestis Endowed with Increased Cytotoxicity Is Avirulent in a Bubonic Plague Model and Induces Rapid Protection against Pneumonic Plague

A Zauberman, A Tidhar, Y Levy, E Bar-Haim… - PLoS …, 2009 - journals.plos.org
An important virulence strategy evolved by bacterial pathogens to overcome host defenses
is the modulation of host cell death. Previous observations have indicated that Yersinia …

Immune Response to Yersinia Outer Proteins and Other Yersinia pestis Antigens after Experimental Plague Infection in Mice

GE Benner, GP Andrews, WR Byrne… - Infection and …, 1999 - Am Soc Microbiol
There is limited information concerning the nature and extent of the immune response to the
virulence determinants of Yersinia pestis during the course of plague infection. In this study …

Characterization of a mouse model of plague after aerosolization of Yersinia pestis CO92

SL Agar, J Sha, SM Foltz, TE Erova… - …, 2008 - microbiologyresearch.org
Yersinia pestis is a Gram-negative bacterium, and the causative agent of bubonic plague
and pneumonic plague. Because of its potential use as a biological warfare weapon, the …

[HTML][HTML] Neutrophils are important in early control of lung infection by Yersinia pestis

TR Laws, MS Davey, RW Titball, R Lukaszewski - Microbes and Infection, 2010 - Elsevier
In this paper we evaluate the role of neutrophils in pneumonic plague. Splenic neutrophils
from naïve BALB/c mice were found to reduce numbers of culturable Yersinia pestis strain …

Kinetics of disease progression and host response in a rat model of bubonic plague

F Sebbane, D Gardner, D Long, BB Gowen… - The American journal of …, 2005 - Elsevier
Plague, caused by the gram-negative bacterium Yersinia pestis, primarily affects rodents but
is also an important zoonotic disease of humans. Bubonic plague in humans follows …

The Resistance of BALB/cJ Mice to Yersinia pestis Maps to the Major Histocompatibility Complex of Chromosome 17

JK Turner, MM McAllister, JL Xu… - Infection and …, 2008 - Am Soc Microbiol
Yersinia pestis, the causative agent of plague, has been well studied at the molecular and
genetic levels, but little is known about the role that host genes play in combating this highly …

Association between virulence of Yersinia pestis and suppression of gamma interferon and tumor necrosis factor alpha

R Nakajima, RR Brubaker - Infection and Immunity, 1993 - Am Soc Microbiol
It is established that Yersinia pestis, the causative agent of bubonic plague, and
enteropathogenic Yersinia pseudotuberculosis and Yersinia enterocolitica share a ca. 70-kb …