Amiodarone, a benzofuranic-derivative iodine-rich drug used mostly for tachyarrhythmias,
often causes changes in the peripheral metabolism of thyroid hormones mainly due to the …

Amiodarone is a benzofuranic-derivative iodine-rich drug widely used for the treatment of
tachyarrhythmias and, to a lesser extent, of ischemic heart disease. It often causes changes …

Although amiodarone is regarded as a highly effective anti-arrhythmic agent, its use may
lead to alterations in thyroid gland function and/or thyroid hormone metabolism, partly …

Amiodarone is a potent antiarrhythmic drug associated with thyroid dysfunction. Its high
iodine content causes inhibition of 5'-deiodinase activity. Most patients remain euthyroid …

Amiodarone blocks the action of thyroid hormone by the inhibition of 5′-deiodinase which
reduces production of T 3 in peripheral tissues and possibly by blocking nuclear binding of T …

Amiodarone (AM), a potent class III anti-arrhythmic drug, is an iodine-rich compound with a
structural resemblance to thyroid hormones triiodothyronine (T3) and thyroxine (T4). At the …

Amiodarone, an iodinated benzofuran derivative, is used for treatment of refractory cardiac
arrhythmias. Certain features of the drug's structure resemble those of the biologically active …

Amiodarone, a benzofuranic iodine-rich antiarrhythmic drug, causes thyroid dysfunction in
15–20% of cases. Amiodarone can cause both hypothyroidism (AIH, amiodarone-induced …

An antiarrhythmic drug, amiodarone, contains 37% iodine by weight and is structurally
similar to the thyroid hormones. The drug inhibits hepatic 5'-deiodinase, resulting in …

Amiodarone, an iodinated benzofuran derivative, has electrophysiologic effects on cardiac
muscle akin to those of hypothyroidism. It is possible that the drug exerts its salutary effect, at …