There is a recognized need to create well-defined polymer probes for in vivo and clinical
positron emission tomography (PET) imaging to guide the development of new generation …

This paper reports the body distribution of block copolymers (made by controlled radical
polymerization) with N-(2-hydroxypropyl) methacrylamide (HPMA) as hydrophilic block and …

Polymeric drug carriers aim to selectively target tumors in combination with protecting
normal tissue. In this regard polymer structure and molecular weight are key factors …

During the last decades polymer-based nanomedicine has turned out to be a promising tool
in modern pharmaceutics. The following article describes the synthesis of well-defined …

Immediately after administration, polymer therapeutics are exposed to complex biological
media like blood which may influence and alter their physicochemical properties due to …

Endocytic uptake and subcellular trafficking of a large array of HPMA (N-(2-hydroxypropyl)
methacrylamide) based copolymers possessing positively or negatively charged residues …

To optimize polymer design for tumor directed drug delivery, the fate and the total body
distribution of soluble synthetic macromolecules, derived from copolymers of [(N-2 …

Copolymers of N-(2-hydroxypropyl) methacrylamide (HPMA) are prototypic and well-
characterized polymeric drug carriers that are being broadly implemented in the delivery of …

Background Polymeric nanoparticles allow to selectively transport chemotherapeutic drugs
to the tumor tissue. These nanocarriers have to be taken up into the cells to release the drug …

This study describes a versatile strategy combining reversible addition fragmentation
transfer (RAFT) polymerization and click chemistry to synthesize well‐defined, reactive …