Members of the nucleotide-binding domain and leucine-rich repeat (LRR)-containing (NLR)
family and the pyrin and HIN domain (PYHIN) family can form multiprotein complexes …

Abstract The NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome is
a multiprotein complex involved in the release of mature interleukin-1β and triggering of …

The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is a multi-
protein complex that can be activated by a variety of pathogen-associated molecular …

Inflammasomes are multiprotein complexes that assemble upon detection of danger signals
to activate the inflammatory enzyme caspase-1, trigger secretion of the highly …

The NLRP3 inflammasome is a critical component of the innate immune system that
mediates caspase-1 activation and the secretion of proinflammatory cytokines IL-1β/IL-18 in …

Inflammasomes are multiprotein complexes that serve as a platform for caspase-1 activation
and interleukin-1β (IL-1β) maturation as well as pyroptosis. Though a number of …

Inflammasomes continue to generate interest in an increasing number of disciplines owing
to their unique ability to integrate a myriad of signals from pathogen‐and damage …

The NOD-, LRR-and pyrin domain-containing protein 3 (NLRP3) inflammasome is a
cytoplasmic supramolecular complex that is activated in response to cellular perturbations …

The NLR family, pyrin domain-containing 3 (NLRP3) inflammasome is a multiprotein
complex that activates caspase 1, leading to the processing and secretion of the pro …

Inflammasomes represent a group of protein complexes that contribute to host defense
against pathogens and repair processes upon the induction of inflammation. However …