When used in the circumstance of preterm labor, is there a paradoxical effect of varying exposures to magnesium sulfate (MgSO4) on the developing human brain?

R Mittendorf, R Besinger, M Santillan… - American Journal of …, 2005 - ajog.org
Objective Given reports of neuropathogenesis following exposure to high dose MgSO4 in
preterm labor (J Pediatr 2002; 140: 540-6; J Perinatol 2005; 25: 101-7), as well as the report …

Randomized controlled trial of magnesium sulfate in women at risk of preterm delivery—neonatal cardiovascular effects

M Paradisis, DA Osborn, N Evans, M Kluckow - Journal of Perinatology, 2012 - nature.com
Objective: Use of antenatal magnesium sulfate (MgSO 4) may reduce cerebral palsy in
infants born very preterm. Low systemic blood flow in the first day in very preterm infants has …

Proximity of magnesium exposure to delivery and neonatal outcomes

AL Turitz, GT Too, C Gyamfi-Bannerman - American journal of obstetrics …, 2016 - Elsevier
Background In infants delivered preterm, magnesium sulfate reduces cerebral palsy in
survivors. The benefit of magnesium given remote from delivery is unclear. Objective Our …

Racial/ethnic disparities in magnesium sulfate neuroprotection: a subgroup analysis of a multicenter randomized controlled trial

G Vilchez, J Dai, K Kumar, D Mundy… - The Journal of …, 2018 - Taylor & Francis
Objective: Despite known racial disparities in obstetrics, as well as differences in
magnesium pharmacodynamics according to race, the effect of race/ethnicity in magnesium …

[HTML][HTML] Effects and safety of magnesium sulfate on neuroprotection: a meta-analysis based on PRISMA guidelines

X Zeng, Y Xue, Q Tian, R Sun, R An - Medicine, 2016 - journals.lww.com
Effects and Safety of Magnesium Sulfate on Neuroprotection:... : Medicine Effects and Safety of
Magnesium Sulfate on Neuroprotection: A Meta-analysis Based on PRISMA Guidelines …

Disparity in post-treatment maternal circulating magnesium sulfate levels between twin and singleton gestation: Is this the missing link between plurality and adverse …

L Marom-Haham, S Mazaki-Tovi… - Journal of Perinatal …, 2015 - degruyter.com
Abstract Objective: Magnesium sulfate (MgSO4) administered to women at risk for preterm
delivery decreases the risk of cerebral palsy in their children. However, the neuroprotective …

Use of magnesium sulfate before 32 weeks of gestation: a European population-based cohort study

HT Wolf, L Huusom, T Weber, A Piedvache… - BMJ open, 2017 - bmjopen.bmj.com
Objectives The use of magnesium sulfate (MgSO4) in European obstetric units is unknown.
We aimed to describe reported policies and actual use of MgSO4 in women delivering …

IS MAGNESIUM NEUROPROTECTIVE TO THE FETUS?† 1324

V Kumar, M Holman, T Rosenkrantz - Pediatric Research, 1996 - nature.com
Maternal administration of magnesium sulfate (MS) has been associated with improved
neonatal survival and lower risk of cerebral palsy (CP). MS blocks the NMDA receptor, a …

Magnesium sulfate and novel therapies to promote neuroprotection

RA Jameson, HB Bernstein - Clinics in perinatology, 2019 - perinatology.theclinics.com
Preterm delivery (PTD) is a major cause of neonatal morbidity and mortality, with surviving
infants at risk for long-term neurologic sequelae. Although any birth occurring before the …

[HTML][HTML] Neonatal effects of magnesium sulfate given to the mother

M Abbassi-Ghanavati, JM Alexander… - American journal of …, 2012 - thieme-connect.com
Objective Magnesium historically has been used for treatment and/or prevention of
eclampsia or preterm labor. More recently, antepartum magnesium sulfate has been …