The chromatin-remodeling enzyme SMARCA5 plays a key role in DNA-templated events
including transcription, DNA replication, and DNA repair. Loss of function of the SMARCA5 …

SMARCA4 is the catalytic subunit of the SWI/SNF chromatin-remodeling complex, which
alters the interactions between DNA and histones and modifies the availability of the DNA …

SMARCA4 encodes one of two mutually exclusive ATPase subunits in the BRG/BRM
associated factor (BAF) complex that is recruited by transcription factors (TFs) to drive …

Endogenous retroviruses (ERVs) can confer benefits to their host but present a threat to
genome integrity if not regulated correctly. Here we identify the SWI/SNF-like remodeler …

SMARCA2 and SMARCA4 are the ATPases of the SWI/SNF chromatin remodeling complex,
which play a significant role in regulating transcriptional activity and DNA repair in cells …

Abstract The mammalian ISWI (Imitation Switch) genes SMARCA1 and SMARCA5 encode
the ATP-dependent chromatin remodeling proteins SNF2L and SNF2H. The ISWI proteins …

Chromatin dynamics influence DNA-dependent processes such as transcription, repair,
replication, and recombination (Hübner and Spector, 2010; Galvani and Thiriet, 2015) …

The SMARCA4 gene codes for a transcription activator protein of the switch/sucrose-
nonfermenting (SWI/SNF) adenosine triphosphate (ATP)–dependent nucleosome …

The genome is wrapped around octamers of histone proteins forming repeating units called
nucleosomes that resemble beads on a string. These structure chromatin, but also present …

DNA wraps around the histone octamer to form nucleosomes, the repeating unit of
chromatin, which create barriers for accessing genetic information. Snf2-like chromatin …