Biodegradable core/shell fibers by coaxial electrospinning: processing, fiber characterization, and its application in sustained drug release

C Wang, KW Yan, YD Lin, PCH Hsieh - Macromolecules, 2010 - ACS Publications
Solutions of two biodegradable polymers, that is, poly (dl-lactic acid)(PDLLA) and poly (3-
hydroxy butyrate)(PHB), were individually delivered to the inner and outer channel of a …

Encapsulating drugs in biodegradable ultrafine fibers through co‐axial electrospinning

ZM Huang, CL He, A Yang, Y Zhang… - … Research Part A: An …, 2006 - Wiley Online Library
This article describes an electrospinning process to fabricate double‐layered ultrafine fibers.
A bioabsorbable polymer, Polycaprolactone (PCL), was used as the outer layer or the shell …

Controlled release of a hydrophilic drug from coaxially electrospun polycaprolactone nanofibers

Z Sultanova, G Kaleli, G Kabay, M Mutlu - International journal of …, 2016 - Elsevier
A recent approach for controlled release of drugs is the production of core-shell fibers via
modified coaxial electrospinning where a shell solution which is not fully electrospinnable …

Coaxial Electrospun Poly(L‐Lactic Acid) Ultrafine Fibers for Sustained Drug Delivery

CL He, ZM Huang, XJ Han, L Liu… - … Science, Part B, 2006 - Taylor & Francis
A coaxial electrospinning technique to fabricate core‐shell ultrafine fiber mats for drug
delivery application is described in this paper. Poly (l‐lactic acid)(PLLA) and tetracycline …

Melt electrospinning vs. solution electrospinning: A comparative study of drug-loaded poly (ε-caprolactone) fibres

H Lian, Z Meng - Materials Science and Engineering: C, 2017 - Elsevier
Curcumin-loaded poly (ε-caprolactone)(PCL) fibres prepared by melt and solution
electrospinning methods were both fabricated to investigate their difference in …

Modulation of protein release from biodegradable core–shell structured fibers prepared by coaxial electrospinning

H Jiang, Y Hu, P Zhao, Y Li… - Journal of Biomedical …, 2006 - Wiley Online Library
Biodegradable core–shell structured fibers with poly (ε‐caprolactone) as shell and bovine
serum albumin (BSA)‐containing dextran as core were prepared by coaxial electrospinning …

Dual-drug encapsulation and release from core–shell nanofibers

Y Su, Q Su, W Liu, G Jin, X Mo… - Journal of Biomaterials …, 2012 - Taylor & Francis
The purpose of this work was to develop a type of tissue-engineering scaffold or drug-
delivery carrier with the capability of encapsulation and controlled release of dual drugs. In …

Effects of drug solubility, state and loading on controlled release in bicomponent electrospun fibers

MV Natu, HC de Sousa, MH Gil - International journal of pharmaceutics, 2010 - Elsevier
Bicomponent fibers of two semi-crystalline (co) polymers, poly (ɛ-caprolactone), and poly
(oxyethylene-b-oxypropylene-b-oxyethylene), were obtained by electrospinning …

Electrospun core–shell nanofibers for drug encapsulation and sustained release

M Maleki, M Latifi, M Amani‐Tehran… - Polymer Engineering & …, 2013 - Wiley Online Library
Fabrication of core–shell nanofibers by coaxial electrospinning system suited for drug
delivery applications was investigated based on tetracycline hydrochloride (TCH) as the …

Investigation of Drug Release and Matrix Degradation of Electrospun Poly(dl-lactide) Fibers with Paracetanol Inoculation

W Cui, X Li, X Zhu, G Yu, S Zhou, J Weng - Biomacromolecules, 2006 - ACS Publications
This study was aimed at assessing the potential use of electrospun fibers as drug delivery
vehicles with focus on the different diameters and drug contents to control drug release and …