Edible plant-derived nanotherapeutics and nanocarriers: recent progress and future directions

N Chen, J Sun, Z Zhu, AP Cribbs… - Expert Opinion on Drug …, 2022 - Taylor & Francis
Introduction High drug delivery efficiency, desirable therapeutic effects, and low toxicity have
become crucial to develop nanotherapeutics. Natural nanoparticles (NPs) from edible plants …

[HTML][HTML] Isolation of cabbage exosome-like nanovesicles and investigation of their biological activities in human cells

JY You, SJ Kang, WJ Rhee - Bioactive materials, 2021 - Elsevier
There are extensive studies on the applications of extracellular vesicles (EVs) produced in
cell culture for therapeutic drug development. However, large quantities of EVs are needed …

[HTML][HTML] Plant exosome-like nanoparticles as biological shuttles for transdermal drug delivery

Y Wang, Y Wei, H Liao, H Fu, X Yang, Q Xiang… - Bioengineering, 2023 - mdpi.com
Exosomes act as emerging transdermal drug delivery vehicles with high deformability and
excellent permeability, which can be used to deliver various small-molecule drugs and …

Application of plant-derived exosome-like nanoparticles in drug delivery

M Barzin, AM Bagheri, M Ohadi, AM Abhaji… - Pharmaceutical …, 2023 - Taylor & Francis
Exosomes are one type of extracellular vesicles with size ranging from 30 to 150 nm, which
are involved in intercellular communication by transporting specific proteins, nucleic acids …

[HTML][HTML] Plant-derived extracellular vesicles and their exciting potential as the future of next-generation drug delivery

FA Alzahrani, MI Khan, N Kameli, E Alsahafi, YM Riza - Biomolecules, 2023 - mdpi.com
Plant cells release tiny membranous vesicles called extracellular vesicles (EVs), which are
rich in lipids, proteins, nucleic acids, and pharmacologically active compounds. These plant …

[HTML][HTML] Milk-derived exosomes exhibit versatile effects for improved oral drug delivery

L Wu, L Wang, X Liu, Y Bai, R Wu, X Li, Y Mao… - … Pharmaceutica Sinica B, 2022 - Elsevier
As endogenous courier vesicles, exosomes play crucial roles in macromolecule
transmission and intercellular communication. Therefore, exosomes have drawn increasing …

[HTML][HTML] Exosome nanovesicles: a potential carrier for therapeutic delivery

VP Chavda, A Pandya, L Kumar, N Raval, LK Vora… - Nano Today, 2023 - Elsevier
Exosomes are small nanosized biovesicles that form when multivesicular bodies and the
plasma membrane fuse and are released into the surrounding body fluids. They are best …

Bioinspired exosome-like therapeutics and delivery nanoplatforms

M Lu, Y Huang - Biomaterials, 2020 - Elsevier
Exosomes have emerged as appealing candidate therapeutic agents and delivery
nanoplatforms due to their endogenous features and unique biological properties. However …

[HTML][HTML] Unlocking the power of exosomes for crossing biological barriers in drug delivery

RO Elliott, M He - Pharmaceutics, 2021 - mdpi.com
Since the 2013 Nobel Prize was awarded for the discovery of vesicle trafficking, a subgroup
of nanovesicles called exosomes has been driving the research field to a new regime for …

[HTML][HTML] Naturally occurring exosome vesicles as potential delivery vehicle for bioactive compounds

P Akuma, OD Okagu, CC Udenigwe - Frontiers in Sustainable Food …, 2019 - frontiersin.org
Various kinds of vesicles have been produced from plant, animal and inorganic materials for
use as delivery vehicles especially in functional food formulation. However, major …