Exosomes and nanoengineering: a match made for precision therapeutics

PHL Tran, D Xiang, TTD Tran, W Yin… - Advanced …, 2020 - Wiley Online Library
Targeted exosomal delivery systems for precision nanomedicine attract wide interest across
areas of molecular cell biology, pharmaceutical sciences, and nanoengineering. Exosomes …

[HTML][HTML] Exosomes as drug delivery systems: endogenous nanovehicles for treatment of systemic lupus erythematosus

A Ortega, O Martinez-Arroyo, MJ Forner, R Cortes - Pharmaceutics, 2021 - mdpi.com
Exosomes, nanometer-sized lipid-bilayer-enclosed extracellular vesicles (EVs), have
attracted increasing attention due to their inherent ability to shuttle proteins, lipids and genes …

Exosomes are endogenous nanoparticles that can deliver biological information between cells

D Sun, X Zhuang, S Zhang, ZB Deng, W Grizzle… - Advanced drug delivery …, 2013 - Elsevier
Exosomal particular size of 30–100nm matches the size criterion for nanoparticles, and
opens up the possibility of using exosomes as a nanoparticle drug carrier. More importantly …

Using exosomes, naturally-equipped nanocarriers, for drug delivery

EV Batrakova, MS Kim - Journal of Controlled Release, 2015 - Elsevier
Exosomes offer distinct advantages that uniquely position them as highly effective drug
carriers. Comprised of cellular membranes with multiple adhesive proteins on their surface …

Exosome-based drug delivery: translation from bench to clinic

HB Koh, HJ Kim, SW Kang, TH Yoo - Pharmaceutics, 2023 - mdpi.com
Exosome-based drug delivery is emerging as a promising field with the potential to
revolutionize therapeutic interventions. Exosomes, which are small extracellular vesicles …

Exosomes as novel bio-carriers for gene and drug delivery

XC Jiang, JQ Gao - International journal of pharmaceutics, 2017 - Elsevier
Clinical treatments have stalled in certain diseases due to a lack of proper therapeutic
delivery systems. Recent studies have identified exosomes for their potential use as cell-free …

Exosomes: the ideal nanovectors for biodelivery

S Fais, M Logozzi, L Lugini, C Federici… - Biological …, 2013 - degruyter.com
Nanomedicine aims to exploit the improved and often novel physical, chemical, and
biological properties of materials at the nanometric scale, possibly with the highest level of …

Cell-derived nanovesicle-mediated drug delivery to the brain: principles and strategies for vesicle engineering

Y Liang, Z Iqbal, J Lu, J Wang, H Zhang, X Chen… - Molecular Therapy, 2023 - cell.com
Developing strategies toward safe and effective drug delivery into the central nervous
system (CNS) with improved targeting abilities and reduced off-target effects is crucial. CNS …

Exosomes: a role for naturally occurring nanovesicles in cancer growth, diagnosis and treatment

A Srivastava, J Filant, KM Moxley, A Sood… - Current gene …, 2015 - ingentaconnect.com
Exosomes are 30-100 nm bodies secreted from almost all types of cells into the extracellular
spaces. They enclose in their lumen active genetic information in the form of messenger …

Biological properties and therapeutic effects of plant-derived nanovesicles

S Di Gioia, MN Hossain, M Conese - Open Medicine, 2020 - degruyter.com
Exosomes-like nanoparticles can be released by a variety of plants and vegetables. The
relevance of plant-derived nanovesicles (PDNVs) in interspecies communication is derived …