[HTML][HTML] The neurovascular unit dysfunction in Alzheimer's disease
LO Soto-Rojas, M Pacheco-Herrero… - International Journal of …, 2021 - mdpi.com
Alzheimer's disease (AD) is the most common neurodegenerative disease worldwide.
Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and …
Histopathologically, AD presents with two hallmarks: neurofibrillary tangles (NFTs), and …
Neurovascular dysfunction and vascular amyloid accumulation as early events in Alzheimer's disease
R Apátiga-Pérez, LO Soto-Rojas… - Metabolic brain …, 2022 - Springer
Alzheimer's disease (AD) is clinically characterized by a progressive loss of cognitive
functions and short-term memory. AD patients present two distinctive neuropathological …
functions and short-term memory. AD patients present two distinctive neuropathological …
[HTML][HTML] Impact of tau on neurovascular pathology in Alzheimer's disease
Alzheimer's disease (AD) is a chronic neurodegenerative disorder and the most prevalent
cause of dementia. The main cerebral histological hallmarks are represented by …
cause of dementia. The main cerebral histological hallmarks are represented by …
New therapeutic targets in the neurovascular pathway in Alzheimer's disease
BV Zlokovic - Neurotherapeutics, 2008 - Springer
Recent findings indicate that neurovascular dysfunction is an integral part of Alzheimer's
disease (AD). Changes in the vascular system of the brain may significantly contribute to the …
disease (AD). Changes in the vascular system of the brain may significantly contribute to the …
Dissecting the contribution of vascular alterations and aging to Alzheimer's disease
C Janota, CA Lemere, MA Brito - Molecular neurobiology, 2016 - Springer
Alzheimer's disease (AD) is a neurodegenerative disease characterized by cognitive decline
that afflicts as many as 45% of individuals who survive past the age of 85. AD has been …
that afflicts as many as 45% of individuals who survive past the age of 85. AD has been …
[HTML][HTML] Role of neuron and glia in Alzheimer's disease and associated vascular dysfunction
S Bandyopadhyay - Frontiers in aging neuroscience, 2021 - frontiersin.org
Amyloidogenicity and vascular dysfunction are the key players in the pathogenesis of
Alzheimer's disease (AD), involving dysregulated cellular interactions. An intricate balance …
Alzheimer's disease (AD), involving dysregulated cellular interactions. An intricate balance …
[HTML][HTML] Blood will out: vascular contributions to Alzheimer's disease
S Strickland - The Journal of clinical investigation, 2018 - Am Soc Clin Investig
The fundamental pathology in Alzheimer's disease (AD) is neuronal dysfunction leading to
cognitive impairment. The amyloid-β peptide (Aβ), derived from amyloid precursor protein, is …
cognitive impairment. The amyloid-β peptide (Aβ), derived from amyloid precursor protein, is …
[HTML][HTML] Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease
AR Nelson, MD Sweeney, AP Sagare… - Biochimica et Biophysica …, 2016 - Elsevier
Vascular insults can initiate a cascade of molecular events leading to neurodegeneration,
cognitive impairment, and dementia. Here, we review the cellular and molecular …
cognitive impairment, and dementia. Here, we review the cellular and molecular …
[HTML][HTML] Neurovascular unit dysfunction and neurodegenerative disorders
X Yu, C Ji, A Shao - Frontiers in neuroscience, 2020 - frontiersin.org
The neurovascular unit (NVU), composed of vascular cells, glial cells, and neurons, is the
minimal functional unit of the brain. The NVU maintains integrity of the blood–brain barrier …
minimal functional unit of the brain. The NVU maintains integrity of the blood–brain barrier …
Molecular links between endothelial dysfunction and neurodegeneration in Alzheimer's disease
E Lyros, C Bakogiannis, Y Liu… - Current Alzheimer …, 2014 - ingentaconnect.com
Alzheimer's disease (AD) is characterized by a progressive decline of cognitive functions
and represents the most common form of dementia and a major cause of morbidity and …
and represents the most common form of dementia and a major cause of morbidity and …
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