The evidence that neurovascular dysfunction is an integral part of Alzheimer's disease (AD)
pathogenesis has continued to emerge in the last decade. Changes in the brain vasculature …

Alzheimer's disease (AD) is the most common form of dementia, affecting millions of people
worldwide. One of the prominent causative factors of AD pathogenesis is cerebral vascular …

Alzheimer's disease (AD) and cerebrovascular diseases share common vascular risk factors
that have disastrous effects on cerebrovascular regulation. Endothelial cells, lining inner …

Aging is the most prominent risk factor for late-onset Alzheimer's disease. Aging associates
with a chronic inflammatory state both in the periphery and in the central nervous system, the …

While prevailing evidence supports that the amyloid cascade hypothesis is a key component
of Alzheimer's disease (AD) pathology, many recent studies indicate that the vascular …

Alzheimer's disease (AD), considered the commonest neurodegenerative cause of
dementia, is associated with hallmark pathologies including extracellular amyloid-β protein …

Vascular dysfunction has a critical role in Alzheimer's disease (AD). Recent data from brain
imaging studies in humans and animal models suggest that cerebrovascular dysfunction …

Growing evidence suggests that vascular perturbation plays a critical role in the
pathogenesis of Alzheimer's disease (AD). It appears to be a common feature in addition to …

Alzheimer's disease (AD) and cerebrovascular disorders are the leading causes of dementia
in our ageing population. Given that the progression of neuropathological changes in the …

There is increasing evidence that cerebrovascular dysfunction plays a role not only in
vascular causes of cognitive impairment but also in Alzheimer's disease (AD). Vascular risk …