The neuropathology of septic shock
T Sharshar, D Annane, GL de la Gradmaison… - Brain …, 2004 - Wiley Online Library
The neuropathological correlates of encephalopathy and autonomic dysfuction in septic
shock are unclear. We performed post mortem analysis of 5 brain areas susceptible to …
shock are unclear. We performed post mortem analysis of 5 brain areas susceptible to …
Neuroanatomy and physiology of brain dysfunction in sepsis
A Mazeraud, Q Pascal, F Verdonk… - Clinics in chest …, 2016 - chestmed.theclinics.com
Sepsis-associated encephalopathy (SAE), a major complication of sepsis, is characterized
by impaired consciousness, including delirium and coma. Additionally SAE associates with …
by impaired consciousness, including delirium and coma. Additionally SAE associates with …
Progress in clinical neurosciences: sepsis-associated encephalopathy: evolving concepts
JX Wilson, GB Young - Canadian Journal of Neurological Sciences, 2003 - cambridge.org
Systemic sepsis commonly produces brain dysfunction, sepsis-associated encephalopathy,
which can vary from a transient, reversible encephalopathy to irreversible brain damage …
which can vary from a transient, reversible encephalopathy to irreversible brain damage …
Apoptosis of neurons in cardiovascular autonomic centres triggered by inducible nitric oxide synthase after death from septic shock
T Sharshar, F Gray, GL de la Grandmaison… - The Lancet, 2003 - thelancet.com
Background Results of experimental and clinical studies have shown that septic shock is
associated with cardiovascular autonomic failure. Thus, we aimed to investigate the …
associated with cardiovascular autonomic failure. Thus, we aimed to investigate the …
Brain lesions in septic shock: a magnetic resonance imaging study
T Sharshar, R Carlier, F Bernard, C Guidoux… - Intensive care …, 2007 - Springer
Background Understanding of sepsis-induced brain dysfunction remains poor, and relies
mainly on data from animals or post-mortem studies in patients. The current study provided …
mainly on data from animals or post-mortem studies in patients. The current study provided …
[HTML][HTML] Science review: The brain in sepsis–culprit and victim
On one side, brain dysfunction is a poorly explored complication of sepsis. On the other side,
brain dysfunction may actively contribute to the pathogenesis of sepsis. The current review …
brain dysfunction may actively contribute to the pathogenesis of sepsis. The current review …
Systemic inflammation induces apoptosis with variable vulnerability of different brain regions
A Semmler, T Okulla, M Sastre… - Journal of chemical …, 2005 - Elsevier
During severe sepsis several immunological defence mechanisms initiate a cascade of
inflammatory events leading to multi-organ failure including septic encephalopathy and …
inflammatory events leading to multi-organ failure including septic encephalopathy and …
The encephalopathy in sepsis
S Siami, D Annane, T Sharshar - Critical care clinics, 2008 - Elsevier
Brain dysfunction is a severe complication of sepsis with an incidence ranging from 9% to
71% that is associated with increased morbidity and mortality. Its diagnosis relies mainly on …
71% that is associated with increased morbidity and mortality. Its diagnosis relies mainly on …
[HTML][HTML] Septic encephalopathy
M Ziaja - Current neurology and neuroscience reports, 2013 - Springer
Every year, more cases of sepsis appear in intensive care units. The most frequent
complication of sepsis is septic encephalopathy (SE), which is also the essential …
complication of sepsis is septic encephalopathy (SE), which is also the essential …
[HTML][HTML] Understanding brain dysfunction in sepsis
R Sonneville, F Verdonk, C Rauturier, IF Klein… - Annals of intensive …, 2013 - Springer
Sepsis often is characterized by an acute brain dysfunction, which is associated with
increased morbidity and mortality. Its pathophysiology is highly complex, resulting from both …
increased morbidity and mortality. Its pathophysiology is highly complex, resulting from both …