Factors predicting response to treatment in rheumatoid arthritis: the importance of disease duration

JJ Anderson, G Wells, AC Verhoeven… - Arthritis & Rheumatism …, 2000 - Wiley Online Library
Objective To use individual patient data from rheumatoid arthritis (RA) clinical trials to
identify factors that affect the response to treatment as defined by the American College of …

Reduction in long‐term disability in patients with rheumatoid arthritis by disease‐modifying antirheumatic drug–based treatment strategies

JF Fries, CA Williams, D Morfeld… - … : Official Journal of the …, 1996 - Wiley Online Library
Objective. Therapeutic strategies for rheumatoid arthritis (RA) have been evolving from the
traditional “pyramid” approach toward one based upon early and sustained use of disease …

American College of Rheumatology preliminary definition of improvement in rheumatoid arthritis

DT Felson, JJ Anderson, M Boers… - … : Official Journal of …, 1995 - Wiley Online Library
Objective. Trials of rheumatoid arthritis (RA) treatments report the average response in
multiple outcome measures for treated patients. It is more clinically relevant to test whether …

Prevalence of and predictive factors for sustained disease‐modifying antirheumatic drug–free remission in rheumatoid arthritis: results from two large early arthritis …

D van der Woude, A Young… - … : Official Journal of …, 2009 - Wiley Online Library
Objective Remission has become an attainable goal of rheumatoid arthritis (RA) treatment,
especially since the advent of biologic antirheumatic therapy. Because little is known about …

The American College of Rheumatology preliminary core set of disease activity measures for rheumatoid arthritis clinical trials

DT Felson, JJ Anderson, M Boers… - … : Official Journal of …, 1993 - Wiley Online Library
Objective. To develop a set of disease activity measures for use in rheumatoid arthritis (RA)
clinical trials, as well as to recommend specific methods for assessing each outcome …

Which outcome measures should be used in rheumatoid arthritis clinical trials?.

R Buchbinder, C Bombardier, M Yeung… - … : Official Journal of the …, 1995 - Wiley Online Library
Objective. To determine the discriminant validity of the core set of outcome measures
proposed by the American College of Rheumatology (ACR) and the Outcome Measures in …

A good response to early DMARD treatment of patients with rheumatoid arthritis in the first year predicts remission during follow up

SMM Verstappen, GA van Albada-Kuipers… - Annals of the …, 2005 - ard.bmj.com
Objective: To describe the frequency and duration of remission in the Utrecht rheumatoid
arthritis cohort of patients followed since diagnosis, and the clinical and treatment …

Analysis of improvement in individual rheumatoid arthritis patients treated with disease‐modifying antirheumatic drugs, based on the findings in patients treated with …

HE Paulus, MJ Egger, JR Ward… - … : Official Journal of the …, 1990 - Wiley Online Library
A composite index for estimating improvement in individual rheumatoid arthritis (RA)
patients during trials of slow‐acting, disease‐modifying antirheumatic drugs (DMARDs) was …

Patient-reported outcomes better discriminate active treatment from placebo in randomized controlled trials in rheumatoid arthritis

V Strand, S Cohen, B Crawford, JS Smolen… - …, 2004 - academic.oup.com
Background. Recent randomized controlled trials (RCTs) in rheumatoid arthritis (RA) have
used patient-and physician-reported outcomes, ESR and/or CRP as components of ACR …

Which traditional measures should be used in rheumatoid arthritis clinical trials?

JJ Anderson, DT Felson, RF Meenan… - … : Official Journal of …, 1989 - Wiley Online Library
It is standard practice to use multiple outcome measures in rheumatoid arthritis (RA) clinical
trials. Because of this, multiple testing is usually done, and there is confusion in the …